6MP x 1 1/2 years now lowered blood counts

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Belle E. Button
New Member

Date Joined Apr 2009
Total Posts : 8
   Posted 4/4/2009 2:20 PM (GMT -7)   
shakehead  This is my first try at this chatting.  I am having some real problems with 6MP.  I started on it 18 months ago at 50mg then upped to 100 mg. 8/08 and upped again to 150mg after a hospital stay and transfusion.  My sedrate and CRP were normal but still my doctor upped all meds, sulfasalazine (6pills/day) 6MP now 150mg and added Entocort (3caps. p/day.  My last 3 labs have shown a decrease in white blood cells, and lymphocyte ABS value.  I am waiting to hear from my doctor.  He last told me not to worry unless my lymphocyte ABS went below 500 and new lab was 480.  I am very worried!  I dropped from 660 to 480 in 5 weeks.  He also ordered a TPMT lab test that had to be sent off.  He said that would determine what level I needed to be at. Why wasn't that checked before I went on this medication?  I think I need to get another doctor involved..I live in Modesto Ca. anyone know of a Good GI doctor in the central valley?  Anyone having this problem with 6MP? 
Belle E. Button  diagnosed 1987. Two sm. bowel resections 1999 and 2005.  Also had a brother with Crohns.

Rider Fan
Veteran Member

Date Joined May 2008
Total Posts : 1445
   Posted 4/4/2009 2:31 PM (GMT -7)   
Are you at 150mg because you are still flaring? Perhaps you just have to stay at 100 and add another medication like a 5-ASA or a biologic. In the past I've been as high as 125mg until my liver enzymes went abit high, then I went back to 100.

Sorry to see the CD is back so soon after surgery, did you get any relief?
32 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira 2/27/09. 17.5mg prednisone. Udo's Choice Probiotics (30 billion). Can't tolerate any iron supplements.

Tried SCD, didn't work, now avoiding gluten and dairy.

Belle E. Button
New Member

Date Joined Apr 2009
Total Posts : 8
   Posted 4/5/2009 10:39 AM (GMT -7)   
My doctor upped the 6MP because of the bleeding problem in February. With my sedrate and CRP normal I'm not sure I was flaring. So that is why I am not sure why all medications were upped. I hope he can explain this and possibly take me off the 6Mp so my labs can get better. Thanks for your response
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