Been on Pred since my early 20's steadily.(35 now) There were times I was able to go off of it for a while, up until about
age 25, then I just could not get off it, without having crohn's symptoms which would destroy any quality of life I had.
The lowest dose that works for me is 15mg every other day. That dose includes taking 100mg of Imuran a day to maintain.
Without Imuran it takes 20mg every other day for me to have some quality of life which is not full of Crohn's symptoms.
To give you a better idea of just how well I respond to Prednisone. In the past, when I have worked, I have upped my dose of pred to 20mg EVERY day, maxing out at 30mg every day, after about
one month of work. After 2-3 months of this dose I would either have to quit my job, or I would have to take a leave of absence so I could get my prednisone dose back down.
I can't do those high doses anymore though. It messes with my sanity WAY TOO much in the form of panic attacks, waves of depression, suicidal thoughts, in short it's not worth it to me, I am able to make it on disability income.
I do ok at 15mg every other day these days, and will proably be going back on Imuran soon. I stopped it due to gallbladder stones, and gallbladder surgery.
The every other day doseage really gives me one day free from taking prednisone, and it is supposed to keep my adrenal glands from burning out, incase one day I am able to get off prednisone completely.(one can still hope)
P.S. I am quite glad that SSRI meds came out, I really benefit from taking celexa, it helps to keep alot of the depression, and other nasty mental issues from prednisone at bay.
CD dx @ 13 (1987)
Prednisone 10mg every other day
Celexa 20mg day
Zantac 300 - Twice Day