Looks like I edited my post too late...
I felt a very slight response to Tysabri, but was never able to taper off steroids. Considering Tysabri's risk for PML is increased by use of other immune suppressing meds, I got nervous and stopped. Actually I think that the patient guidelines would not have allowed me to continue past the 6 months if I failed the taper.
Oh, and steroids are acceptable on Tysabri, but the patient is supposed to be able to taper...
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine --rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08 => STOPPED 10/3/08 not enough response
--currently taking budesonide suppositories, 3mg at night. Started Cimzia first dose 2/10/09. Dx Osteoporosis 10/08 started Forteo 1/27/09
--single mom to 11-yr-old girl