Blood Work Results - Positive Antibodies

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Regular Member

Date Joined Mar 2007
Total Posts : 31
   Posted 5/5/2009 11:33 AM (GMT -7)   
A few years ago the Dr. tested my blood for antibody markers and he said they were positive, and made the Crohns diagnosis based on that and my awful symptoms. I then did the colonosocopy and they didn't see anything from - so I was kinda "unofficially undiagnosed."
Fast forward to present day, all of a sudden all of my symptoms come back (since April 1st) and the Dr. runs the lab work again - once again I test positive for the antibodies.
What does all of that mean - what does the blood work do in terms of diagnosing?
Thanks Everyone - I love this site!

Veteran Member

Date Joined Nov 2007
Total Posts : 4413
   Posted 5/5/2009 12:25 PM (GMT -7)   

The doctor can't always diagnose Crohn's from a colonoscopy alone, since in a colonoscopy they can only see your large intestine and sometimes part of the terminal ileum.  There are other tests that can visualize your small intestine such as swallowing barium and watching by x-ray for it to pass through your small intestine, or the camera swallow test, where you swallow a camera the size of a pill and it transmits images throughout your entire GI system.  Soemtimes they can also do a CT scan of your abdomen, and can visualize strictures, fistulas, and blockages that way.  Go to the website (Crohn's foundation) and you can read about all of the diagnostic tests.

The doctor didn't see anything on my first colonoscopy, but was able to biopsy a part of my terminal ileum the following year and was able to confirm the blood results.  Good luck, and don't stop asking questions!

50 yr. old female, diagnosed with Crohn's in small intestine and terminal ileum Sept-Oct. 2007. Also have IBS, and had Salmonella Dec. '07
currently taking Pentasa- 4 500mg pills per day, Metamucil and colace for constipation

Regular Member

Date Joined Apr 2009
Total Posts : 47
   Posted 5/8/2009 6:25 AM (GMT -7)   
Hey There, Same problem,
I've been sick for 3 yrs and tons of test, I recently had my MD do blood work and it was postive also and very high, Went to GI dr. who I left very upset. They told me they do believe in those blood test. Well I know I have crohns, I actually go today for a CT abdomen with constrast per GI since it's been over a yr. I am having severe lft side pain and swelling and bloating and following and chron's diet which has helped. Anyways, depending on what they find or not I will go to another GI dr.Chrons is auto-immune and my mom, 2 aunts(her sisters) and cousin all have auto-immune diseases which puts me at higher risk.
You dont just have HIGH IGG and IGA for know reason, and my GI dr's pretty much dont believe in the blood test and blew it off. I work in the medical field and the one thing I learned is you dont give up until you find the right dr who will listen to you. Good Luck.
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