Imuran dosage (UPDATE!)

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Veteran Member

Date Joined Mar 2007
Total Posts : 1799
   Posted 6/23/2009 6:14 PM (GMT -7)   
Sorry to post the same thread again, but we got some confusing imput tonight from the Pharmacist. I filled a new prescription, and he told us that the blood work for the optimal dose may not be accurate because she is taking the Imuran with an Iron supplement. He said that Iron bonds with certain medications and weakens there effectiveness.
Has anyone ever heard of this? I'm not sure if we should increase the dose now, but I will call the GI in the morning to inquire about this.
My daughter was diagnosed Feb. 19/07, (13 yrs. old at time of diagnosis), with Crohn's of the Terminal Illium. Has used Prednisone and Pentasa. Started Imuran (02/09), had an abdominal abscess (12/08). 2cm of Stricture.

Regular Member

Date Joined Jul 2008
Total Posts : 440
   Posted 6/23/2009 7:14 PM (GMT -7)   
I have heard of to your GI but, your pharmacist could actually be the brighter one here....good luck

 41 yr old woman with 12 surgerys under my belt. Diagnosed in 2005 CD. PTSD 1999. Gullbladder taken 2000, Hysterectomy 2005, Back surgery 1998 with herniation L-4, L-5, S-1. Two-Re-sections on small intestine, total of 18 inches taken out 2006. Stomach Herniation from re-section 2007, Been getting kidney stones too! The good news...finding this website.
                Meds: Imuran 200mg daily, asacol, Bentyl, Coelestid, occasional flagyl and cipro, high blood pressure meds, paxil 25 mg, 4/20meq's potassium, synthroid...& try to get alot of laughter in.

Veteran Member

Date Joined Dec 2008
Total Posts : 947
   Posted 6/23/2009 8:07 PM (GMT -7)   
I have not heard of this, but flowery is right the pharmasist is probably brighter.
Diagnosed with Crohns in 2001
First and hopefully last Ileocecectomy 2/18/2009

Medications: Asacol, Precription Folic Acid, Multivitamin, 1000mg Calcium, Vitamin D, Probiotics,  Monthly B-12 injections.

Living a Great life with my Wife and my two Chocolate Labs
Hunter & Hailey.
I love them dearly.

Rider Fan
Veteran Member

Date Joined May 2008
Total Posts : 1445
   Posted 6/23/2009 8:18 PM (GMT -7)   
Never heard of that, very interesting.
32 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira 2/27/09. 5mg prednisone. Udo's Choice Probiotics (30 billion). Can't tolerate any iron supplements or infusions.

Tried SCD, didn't work, now avoiding gluten and dairy.

Go Saskatchewan Roughriders!

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 6/24/2009 1:42 AM (GMT -7)   
Yep, I agree with the others. I'd talk with the doc, as pharmacists can be pretty cluey and know things that doctors don't.
Co-Moderator Crohn's Forum.

New meds thread

Veteran Member

Date Joined Apr 2006
Total Posts : 1885
   Posted 6/24/2009 9:48 AM (GMT -7)   

Veteran Member

Date Joined Mar 2007
Total Posts : 1653
   Posted 6/24/2009 11:36 AM (GMT -7)   
I haven't seen any research on this, nor has it come up at the conferences I've been to.

I suppose there is a hypothetical possibility, but to me that would mean following the metabolite blood tests for the optimum dose would be *more* important, not less so. If iron is affecting imuran absorption, the metabolite tests would show it; they wouldn't become less accurate because of this.
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