I got taken off of the Cimzia yesterday. I'm back on Humira(which I had been on for 2 years until it stated to loose its effectiveness.) The Cimzia seemed promising at first. After the two loading doses I had two whole days with only 4 bms! I was so thrilled. I have been flaring for close to five years. Humira was the best up to that point. The remicade seemed promising as well but I developed pneumonia(never had it before)and was hospitalized for 6 days. Prior to that was methotrexate, asacol. entocort, pentassa. All of these including the Cimzia have been in conjunction with prednisone. The reason for stopping the Cimzia was the side effects. Abdominal pain was brutal, muscle fatigue minimal, minimal headache. The bigger issue is that like many others here I have had chronic fungal infections particularly thrush/Candidas. Nystatin has always done the trick for me and I have gotten used to the routine. After my third dose I develpoed a rash on my back and arms. I have for sometime had a similar rash that we diagnosed as Grover's disease and the side effects of prednisone. I was sent to see an infectious disease Doc. Who pointed out a couple of small papules on my leg arm and jaw. tehse were not like the others(possibly Hepatitis). He did cultures and the diagnosis is that the Candidas has spread throughout my system(didn't klnow it could)a suppossedly to my liver. Lver biopsy coming. I am telling you that I have had some very good luck with some of the Crohn's meds and I have had some bad luck. I no way think this reaction is normal for most people. The Cimzia is also like the Humira which to date has worked the best for me. Teh problem for me is that the Cimzia was not lasting more than three days and with the shots spaced a month a part there is no way I could do it. At least the Humira I can inject myself at home 1x weekly. I get about
3-4 days from that. It is very easy to find all the reasons that we don't want to take or med or why we may be nervous. I have been this way for some time but the reality is I'm not able to do anything without these meds. I guess what I am trying to say is that the previous posts have mostly had success. Simplicity the company that distributes the med. give you a handy log book or binder. In it there are pages for you to chart you symptoms and reactions. Don't hesitate to call the nurses at Simplicity. They are very nice and more than willing to help. Make sure to call the doctor if you find something or experience something that you don't think is right. In my case the doc and I both agree that for some reason the Cimzia enhanced what was already there ie the Candidas, hepatitis and so on but please keep track of these things it is important. If it's not working the way the doctor says it should call them.
Good luck and please let us know how you are doing.
P.S. Humira pens burn much worse than Cimzia. I barely felt the Cimzia
Formal diagnosis 3/2006, IBS 1992, Degenerative Arthritis Facet block and RFA, Seizure Disorder, Severe Carpal Tunnel both hands, SVT arrythmia, 2004 cardiac Ablation
Cushings Syndrome(thanks Prednisone), Asthma, Multiple Laps for ovarian adhesion to bowel, C/5 & 6 disc herniation - plate with screws, resistant to anethesia/most pain meds. Chronic fungal infections.
Multitude of Meds. Have tried most Crohn's meds. Gall bladder removal and Intestinal Lap. June 08.- Intestinal blockage July 08 moved on from on Humira..now on Cimzia.