Mezavant (mesalazine)

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New Member

Date Joined Aug 2009
Total Posts : 5
   Posted 8/6/2009 3:38 PM (GMT -7)   
Hi all,
I'm new to the site, though I've been reading bits of it over the last few months...  I'm not sure where to start!  I have been unwell with Crohn's type symptoms since October last year, diagnosed with potential Crohn's in March this year.  Part of the trouble I have is that I have frequent bowel motions, always urgently after breakfast, and often after eating.  It seems to be worse on an empty stomach (hence the breakfast problems).  I'm on a wheat free diet, which seems to be of some help.  Anyway, I just wanted to know if anyone else had similar problems with eating and then needing to pass stools urgently?  I feel like my body is rejecting food.  Is this typical of Crohn's disease?  Or it is possible that it's a side effect of the Mezavant medication I am taking?  (I didn't have this problem before I started taking the meds, just other Crohn's symptoms).  I'm concerned that it's the medication making me unwell and not the condition itself, and I don't know how to tell what's due to what!  Any advice would be gratefully received!
Thanks and regards


Regular Member

Date Joined Apr 2009
Total Posts : 166
   Posted 8/6/2009 7:45 PM (GMT -7)   
I had trouble with Mezavant also. It made me sick. You must take it with food, and not just a cookie apparently. I liked the idea of 1 pill once a day, but it didn't work for me. My GI said that I was his first patient to try on it, and also the first to have problems with it. He had heard of quite a few others after me. That is not to say that the medication is no good, just that you must take it a directed because it is less forgiving than other types apparently.
44 years old. Diagnosed with moderate to severe Crohn's in April 2005. Hiatus hernia diagnosed in 2008. Had Crohn's under control until March this year when I had a major flare up and ended up in hospital. Diagnosis is now CD and IBS. Getting it under control again.
Currently taking: Prednisone 5 mg, Salofalk 2000 mg, Nexium 40 mg, Calcium and Vitamin D, Matamucil, Yogurt for probiotics, Salofalk suppositories as needed.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 8/7/2009 6:24 AM (GMT -7)   
Could very well be the medication, but it also could be GERD/Acid Reflux. I had similar symptoms and thought my Crohns was acting up and it was actually GERD. Just another thought!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed for my anxiety.  Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*
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