Delayed prednisone side effects

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Regular Member

Date Joined Aug 2009
Total Posts : 377
   Posted 8/11/2009 12:08 PM (GMT -7)   
I was just diagnosed with Crohn's last month. Initially I was put on Prednisone, 40 mg. It helped bring down the inflammation a bit, but I ended up back in the hospital, because I wasn't getting any better. When I started, I didn't seem to have any significant side effects.

I am currently tapering and am down to 20 mg now. However, now I feel like I am starting to feel some side effects, such as insomnia and extreme hunger. I'm not sure if the hunger is due to the prednisone or because I have ramped up my exercise routine. I've tried limiting my carbs to see if that helps, but I'm so hungry I feel like I could eat a horse.

Is it normal to have delayed side effects even while tapering?

Anyone who experiences extreme hunger with prednisone, do you have any suggestions on how to combat it? I've gained some weight since I've been out of the hospital, and I needed to, but I don't really want to gain any more. It's hard not to eat so much though when you feel like you're starving all the time.

Veteran Member

Date Joined May 2009
Total Posts : 506
   Posted 8/11/2009 1:03 PM (GMT -7)   
I've had extreme hunger and insomnia each time I've been on pred. I believe mine started within a few days of starting the drug, but got worse as I went along, until I was nearing the end of the taper. Not sure there's any way to combat either. Or if there is, I've never heard of it.
Diagnosed with CD July 2007
Currently on Remicade, Imuran, probiotics, folic acid, multivitamin.

Veteran Member

Date Joined Mar 2006
Total Posts : 1354
   Posted 8/11/2009 8:04 PM (GMT -7)   
I find Im always starving on pred no matter how low a mg Im on. I try to drink lots of water and battle with myself that 'Im not HUNGRY" or nibble on crackers.:)

Regular Member

Date Joined Nov 2007
Total Posts : 41
   Posted 8/11/2009 8:13 PM (GMT -7)   

My GI explained the pred to me as this:  It takes a few days to a few weeks for the pred to build up in your system, therefore, when you are tapering, the effects (hunger, insomia, etc) will last a while.  Just hang in there!!!  This too should pass, at least for a while altho some of my "belly" is still hanging around!  Hope you feel better soon.


remember to always take your rainbow with you........

Regular Member

Date Joined Aug 2009
Total Posts : 31
   Posted 8/11/2009 8:48 PM (GMT -7)   
I gained weight too when I was on prednisone because I felt hungry all the time. Just be careful and think why you are eating. Also try drinking water before you eat it will help fill you up.
Crohn's disease, currently no medications, 2 surgeries, ostomy since 2004

Regular Member

Date Joined Jul 2009
Total Posts : 342
   Posted 8/17/2009 10:45 PM (GMT -7)   
I have taken this drug many times..each time..the side effects were different for me..the first tine i helped alot and i gained a few doctor combat the hunger only eat the three normal meals a day..if you were eating alot of puffed rice or carrots or celery sticks..the weight might not come on as fast..recently when i was taking it..i had the insomnia but also i had no appetite and i couldn't eat and i lost 6 pounds....i suggest you drink water and chew gum..that might help

Post Edited By Moderator (Nanners) : 8/18/2009 7:31:04 AM (GMT-6)

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