I've gone through the same question with my daughter. She was diagnosed last October, she was 10 (has since turned 11), we've been through the whole realm of meds, including remicade. Her first 2 infusions went great, she had a reaction to the third one, trouble breathing, throat closing up on her, very scary. We just went on the 12th (august) to try another infusion. Premedicated with tylonal, benedryl, solumedrol and she had a reaction after received 1 tsp of remicade. I cant tell you how stressed I've been about reading about TB and Lymphoma. I hate it. Part of me is glad she had the 2nd reaction so we can stop it, and she is doing very well right now, but now I'm stuck with, what happens when things go downhill? The next med is humira, not FDA approved for kids. HELLO, I want nothing to do with that. We have since tried going a more natural root. She is taking colazol and cipro right now along with fish oil and total balance vitamins (order online) and she seems to be doing pretty good. We are going to start Reiki sessions, of which I have always laughed at Reiki, but when its your childs health, you'll try anything - within reason. I worry now that my daughter had reacted to the remicade, that she may be more suseptable to contract some of the bad side effects. I know how hard it is. I've had many sleepless nights, many nights in the hospital (2 weeks in January). My daughter lost 12 pounds in 3 weeks last summer, which prompted the colonoscopy, i knew it wouldn't be good, my father had his colon removed 10 years ago due to diagnosis. Anyone who reads this who has a child on humira, I'd love to hear from you because I am just not willing to go there right now.