questions re cipro and flagyl

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Regular Member

Date Joined Aug 2009
Total Posts : 41
   Posted 8/26/2009 8:13 AM (GMT -7)   
Hey everyone,
I'm new here, and so glad to have found some support and people who have gone through the same things I have!! 
I wrote up my history in a previous post, so I won't go all into it again- but I had surgery this year to drain a "chronic rectal abscess" that went undiagnosed for 3+years.  I felt pretty good for a few weeks, and then they went in again to address the old abscess spot and a bump/swelling to the right of my rectum, that goes almost up to my tailbone- maybe 2 1/2 inches long and 1/2 inch wide. My CRS says he thinks this spot is inflamed tissue or muscle, not an abscess, although he admits he is not sure. He did put me on cipro and flagyl for two weeks to see if this helps. I feel like a new woman, after only 6 days on the new pills!
I had been having diarrhea since my last surgery, and this stopped literally 12 hours after my first doses of the antibiotics. My pain and pressure have also subsided significantly, as has the swelling. The bump itself is almost completely gone, I can still feel it but it is tiny. I can actually sit in my chair in my office without contorting my body :)

So my questions: he had wanted an MRI next week, but I'm wondering if this is the best time, since I am feeling so much better from the antibiotics? Typically what happens is that after I go off the antibiotics, I slowly start to feel worse and the pain comes back. It is always in the same place, hasn't changed in 3 1/2 years, which makes me almost positive it is another small abscess, or as someone in a previous post said "encapsulated infection." This would be my third MRI in two years, and I'm thinking it may be more helpful to see what happens when I go off the antibiotics... hoping for the best but also prepared for what has always happened.
What do I do? Also any thoughts on why after only 12 hours the diarrhea was gone? Does this sound like a Crohn's abscess/fistula?
Thanks in advance for any guidance!!

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 8/26/2009 8:44 AM (GMT -7)   
I think I would go ahead with the MRI myself, in my opinion better safe than sorry. Sense it seems to come back shortly after the abx, it probably is best to get the MRI to get a better look at the area. I was recently put on Cipro for a small intestine bacterial overgrowth, and I was so surprised how quickly I started feeling better. I think in my case, it was the next day. I was also surprised I didn't get any diarrhea from the anti-b's at all either. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined May 2007
Total Posts : 1220
   Posted 8/26/2009 11:53 AM (GMT -7)   
I also would get the MRI. It can't hurt to have a scan while on antibiotics. I am so glad you are doing better!

These drugs can wickedly mess with your head, but gosh they really do work!! I thnk you may need a longer course of antibiotics. Every time I went off, it flaired up again. Then I stayed on for several months and that finally did the trick. What a relief!! My surgeon didn't really understand this, but my GI did. Makes sense because surgeons cut, but GI's treat long-term. My GI said many of his CD patients are on cipro long-term. Even though the drugs are nasty, a long course of them may rid you of this completely!! And hopefully you will get on remi and eventually it will heal/shrink that fistula. And both of these antibiotics help reduce inflammation, so maybe that is helping with the diarhea.
Diagnosed with Crohn's in early 2007.  Several peri-rectal abscesses and two fistulae with setons.  Allergic to Remicade and Humira.  Currently on 6MP, and vitamins D and B-12.

Veteran Member

Date Joined Apr 2005
Total Posts : 3763
   Posted 8/26/2009 12:31 PM (GMT -7)   
When I was first diagnosed it was with fissures and fistulas. I ended up on Flagyl for months. It did the trick. I"m just saying that you may need to be on these meds for a more extended period of time. I too would proceed with the MRI to see what is going on while on the antibiotics and then if things to kick up when you stop, then you will have something to refer back to.

CD 20 years officially, 30 unofficially. 3 resections '93, '95 '97
Managing with strict low residue diet, keeping symptoms to a minimum. All test show small amount of ulceration, still have occasional blockages. But still have a great time with my 2 daughters and husband!

Prednisone, 6MP,Prevacid, B12 shots, Bentyl, Xifaxan.....

Regular Member

Date Joined Aug 2009
Total Posts : 41
   Posted 8/26/2009 2:22 PM (GMT -7)   
Thanks everyone. I was just wondering if I have the MRI next week when I am feeling better, if it will show anything different than the one I had in May. If I flare up again or the pain comes back (which it always does), will they want to do another MRI or just wait and see... I've had enough of waiting and seeing! Not sure how many MRI's my insurance will pay for...
Is there no definitive way to diagnose small abscesses and fistulas? Mine only showed up vaguely on an ultrasound, never on MRI or CT.
Here's to feeling better :) Even if I have a really short temper lately (totally get the messing with your head part.)

Veteran Member

Date Joined Sep 2005
Total Posts : 769
   Posted 8/26/2009 4:14 PM (GMT -7)   

I was on flagyl and amocycillin for almost a yr with an abscess, waiting for surgery and healing etc….. I went off it at one stage after my seton was 1st inserted and the sepsis returned so fast it wasn’t funny……. So I hopped back onto the antibiotic bandwagon. I know that when I was taking 3 flagyl a day I had a lot of nervousness and anxiety issues, but on 2 a day I was fine. Also on 3 a day (which is an aggressive dose) I had no appetite and felt nauseas nearly all the time….


I remember the 1st week I ever took the antis in a combination like that – I remember thinking I had SO much more energy at work, didn’t need to sleep so much, and my tummy symptoms really improved and I was less sensitive in relation to what I could eat etc….. I think the antis were killing off an overgrowth of bacteria as happens in us chronnies….. My symptoms got better all round. Unfortunately when I went off the antis the worse symptoms returned. Now I am waiting on my first dose of Remicade and hoping it will held heal my fistula….. I still have the mushroom drain in my abscess…..

Regular Member

Date Joined Jul 2009
Total Posts : 342
   Posted 8/27/2009 12:37 AM (GMT -7)   
I would get the MRI as well..if the cavity.from the prior abscess is still inside of you..then its you can pretty much count on the fact that the abscess can collect in that spot again....i was cut in near the tailbone first time myself...too this day i still having trouble sitting..sometimes its uncomfortable near the incision..but never a me that indicates...infection..or inflammation..and infection must be drained at all times..and inflammation can lead to fistula's..which are often the cause of the abscess to begin with...I am taking cipro and flagyl myself..and they both do deal with infection..but you still have to get it out of the body..on the bright side..i can tell you that an MRI was 100% correct in identifying my i believe you will find some answers...after you get it..good luck and i wish you well

 crohns/colitis/lupus/hyperthyroidism-seton fistula pentasa cipro flagyl vicodin

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