I actually have heard of Tysabri. My best friend has MS and is currently on Tysabri to control her relapses. Although the drug has been approved for Crohn's treatment, this drug does have alot of unwanted side effects. Tysabri is a last resort drug because it breaks down the blood brain barrier, which protects your brain from infections. This is most definitely not a good thing, and would make me very hesitant to even go on this drug. Tysabri has been directly linked with the brain infection, PML, which is not cureable and will cause death. This drug has not been studied in patients who have been on it over 2 years, and those patients that have been on it for over 2 years have eventually acquired PML. I would definitely read up on what this drug can do for you and then talk to your doctor.
I was in your position. I stopped responding to the remicade, and my doctor told me that Humira and Czima only had a 25% of working. I ended up with a bowel resection in 2007, and my crohn's came back 6 months later. I am currently on Humira and have responded incredibly well to it. I did study abroad for a semester in Italy before my resection, when my crohn's was very much active. Because their food is all fresh, my crohn's was in heaven and I did not have one problem while I was over there. When I came back it was a different story.
-Heather, 24 yrs. old
- Crohns disease since 1995, officially diagnosed in 2003.
- Bowel resection in Dec. 07, Crohns reoccurred July 08.
- Medications - Entocort 9mg, Humira, Flagyl 250mg, Lexapro 20mg, Wellbutrin SR 150mg