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Regular Member

Date Joined Sep 2009
Total Posts : 212
   Posted 11/22/2009 5:56 PM (GMT -7)   
Can anyone tell me what form the 6-mercaptopurine usually comes in?  Is this a tablet, capsule, liquid?  How big is it?  Just trying to get an idea of whether or not my daughter would be able to swallow it, if it is prescribed. Thanks.

  • BWS27
    Regular Member

    Date Joined Nov 2009
    Total Posts : 37
       Posted 11/22/2009 6:31 PM (GMT -7)   
    Hello Mooby~

    I take two 50mg tablets of 6-mp a day. They are about 1cm in diameter and fairly easy to swallow. However, they do disolve failry fast in your mouth so no messing around once you pop them in! Good luck, let us know if it works for her!!
    28 year old husband and father of 1 (soon to be 2!!), Diagnosed with Crohns and resection surgery in Jan '09 (same ER trip), currently not winning the battle with pain, taking: 6mp, Pentasa, Prednisone and every vitamin possible! 

    What lies behind us and what lies before us are tiny matters compared to what lies within us." -- Ralph Waldo Emerson

    New Member

    Date Joined Aug 2009
    Total Posts : 17
       Posted 11/22/2009 7:10 PM (GMT -7)   
    My daughter started with one 50 mg pill.She is 11 and around 95 pounds.Unfortunately she had bloodwork done that showed it was too high a dose for her and could cause some problems in the future.She needed to go to 40 mg.Of course we cant get it in pill form so we had to find a compounding pharmacy that would make it. The store pharmacies like Giant,Weis and the Cvs stores dont do this.We had to go to a small local pharmacy and they have made it for us.They do add flavoring to it for the kids but it is still a little bitter. Any other questions just ask.

    New Member

    Date Joined Aug 2009
    Total Posts : 13
       Posted 11/23/2009 2:21 PM (GMT -7)   
    I have been on 6mp for quite some time. One tablet a day with other meds. However, with that I need a blood test every three months to check the liver.
    Better ask the Doctor about that.
    Had Crohns' since I was in my early twentys and now am 65 years old. On Mercaptopurine 50mg and Balsalazide 750 mg. I am lucky from what I have been reading. No bowel resection yet and it has been a while since a flare.

    Veteran Member

    Date Joined Apr 2005
    Total Posts : 3763
       Posted 11/23/2009 3:19 PM (GMT -7)   
    As the others posted, 6MP is prescribed somewhat by your daughter's weight, but it will also be decided by how she is tolerating the medication and how her liver is metabolizing it. That is one of the reasons for all the blood work. The original dose should be weight based. Then the blood work starts. At some point you should ask to have the blood sent to Prometheus to check for the therapeutic levels as well as the toxic levels. They are the only lab that can do the therapeutic levels. If your daughter isn't at the therapeutic level yet, then the dose can be increased if the toxic levels are OK. And if the toxic levels are too high, but she is in the therapeutic levels, they can lower the dose. It is all a bit of a game in the beginning. I have been on doses as high as 150mg and as low as my current dose of 50mg within the span of about 12 years. Just make sure that you keep up with blood work and request to have it sent to Prometheus occasionally, but get prior approval from your insurance for that one!

    CD 20 years officially, 30 unofficially. 3 resections '93, '95 '97
    Managing with strict low residue diet, keeping symptoms to a minimum. All test show small amount of ulceration, still have occasional blockages. But still have a great time with my 2 daughters and husband!

    Prednisone, 6MP,Prevacid, B12 shots, Bentyl, Xifaxan.....

    Veteran Member

    Date Joined Jan 2007
    Total Posts : 656
       Posted 11/23/2009 3:19 PM (GMT -7)   
    I take one 50mg pill a day. The pill is round and pretty small--not big like a multivitamin. And yes, I do have to have a liver function blood test every quarter. Definitely talk to your doctor about that, since it will not be fun for her.

    Regular Member

    Date Joined Sep 2009
    Total Posts : 212
       Posted 11/23/2009 4:57 PM (GMT -7)   
    Well she is only 63 lbs. so I'm guessing her dose would be pretty minimal.  As for bloodwork, she's an old pro at that, at only 9 years old. She doesn't enjoy them, but they don't scare her the way they used to. Her doc has been checking her blood on a fairly regular basis since this all began last winter. She's had bloodwork done about 5-6 times now so if that's our biggest obstacle, we'll take it.
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