Pentasa not digesting?

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

New Member

Date Joined Sep 2009
Total Posts : 11
   Posted 11/25/2009 5:06 PM (GMT -7)   
So I have been on entocort for about two months to help get me out of a flare and two weeks ago they decided to try pentasa (which hasn't worked in the past) in an effort to avoid 6mp and since starting it I keep having lots of tiny white bead looking things in my poo and I broke open one of the pentasa capsules and it is the stuff inside of it that is coming out. I was wondering if anyone else has the same thing or if maybe it might mean they are not digesting?
Crohn's for 8 yrs; entocort ec 3 mg 3daily,
pentasa 500mg 2 3x daily,vitamin D & Calcium

Regular Member

Date Joined Oct 2009
Total Posts : 253
   Posted 11/25/2009 5:25 PM (GMT -7)   
I have that too, I'm asking my doctor about it next week along with some other questions about possible side effects... I'll post here if she says anything relevant!
19 y/o female, diagnosed crohns december 2008
currently taking 500 mg pentasa 4x daily

Forum Moderator

Date Joined Nov 2003
Total Posts : 7122
   Posted 11/25/2009 5:42 PM (GMT -7)   
Pentasa and Asacol are formulated to be released lower in the intestinal tract. The white beads are what contain the medication. The medication is released from the bead leaving the outer shell. That is what you are most likely seeing.

That said, it is possible to pass medications both time released and "regular" without then delivering the medication. I have passed two different medications intact. When I was having severe diarrhea, over 20 times, a day, I also experienced loss of bowel control. I once found my blood pressure medication in my underwear about 6 hours after I took it,

I used to take a time released asthma medication. I often would see it in my stool. The doctor assured me that I was seeing the shell of the medication. However, my asthma was getting worse so I decided to investigate. I fished out the pill the next time I saw it and broke it open. It contained all the medication. This instituted an investigation by the pharmaceutical manufacturer. They discovered that my GERD pill, Prevacid, was inhibiting my acid production which the medication needed to start the process to dissolve.
Moderator Crohn's Disease  & Osteoarthritis Forums
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, asthma, severe allergy and a host of other medical problems.

Veteran Member

Date Joined Apr 2008
Total Posts : 1753
   Posted 11/25/2009 5:53 PM (GMT -7)   
That's actually normal so you really don't have anything to worry about. While the rest of the medicine has been administered where it needs to be, this particular part is not meant to stay or "disappear" in your system.

So, no worries :)
Diagnosed with Crohn's in May of 2008.
Currently taking: Prednisone, pentasa, omeprazole, and humira. Using probiotics and a multivitamin.
Learning how to live again.
"He who has a why to live for can bear with almost any how."

Veteran Member

Date Joined Mar 2009
Total Posts : 1118
   Posted 11/26/2009 5:27 AM (GMT -7)   
Hi i too take Pentasa but not in capsule form, the ones i take you can just swollow or put them  a in a small amount of water and take maybe this would be better for you than the capsules Bevx 
Diagnosed with crohn's at 13 now 42
resection, right hemi 1993 In remmision from 93 till last sept with no meds or docs
2 resections small bowel  and fistula jan 09 and given temp stoma.  reversal 1st week of Jan. Meds:Pentasa 500mg 3x day,  B12 shots, every 3 months, iron syrup,loperimide,folic acid,  citalopram 60mg (for Anxiety.)

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 11/26/2009 8:50 AM (GMT -7)   
Seeing the beads as Ides said is normal. No worries. I take the sister med Asacol and I always see the shells in my stools. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Regular Member

Date Joined Jul 2009
Total Posts : 342
   Posted 11/26/2009 1:00 PM (GMT -7)   
its just the shell...its a pain..i didn't like it..since Remi i refuse to take my caused so many problems as it used to get stuck in my fistula...i think its not good for those who have fistula's....i have had them getting stuck in skin next to where my fistula used to drain..and i don't know why..but it made me hate Pentasa..i think Asacol works better..i might go back on that..i just need to call my GI..

 Crohn's Lupus Hyperthyroid..Pentasa Remicade Fistula tag removed!


New Member

Date Joined Sep 2009
Total Posts : 11
   Posted 11/27/2009 5:11 PM (GMT -7)   
Thanks everyone I feel alot better now. I appreciate you all taking the time to respond! smilewinkgrin
Crohn's for 8 yrs; entocort ec 3 mg 3daily,
pentasa 500mg 2 4x daily,vitamin D & Calcium

Regular Member

Date Joined Mar 2008
Total Posts : 155
   Posted 11/28/2009 10:46 AM (GMT -7)   
Pentasa didnt work for me, either. But I was having my diabetes medicine passing through whole. so we had to change to insulin.
take care.
Diagnosed  Crohn's, 1998..Gangrene Small Bowel,1998..Ostomy Take Down,1999..TPN for 5 1/2 months..Adhesion Removal,1999..Abdominal Hernia Repair,2000..Kidney Artery Bypass,2001..Diabetes,,Sleep Apnea,,Silent Heart Attack,,Blocked Kidney Artery after the Bypass..Bulging Disks, Pinched Nerve..MEDS--,Purinethol,Folic Acid, Fish Oil,Humira,,Bentyl,Anamantle Cream,Cortifoam ,Tramadol, .and many more. 29 meds..
New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, January 19, 2018 8:14 PM (GMT -7)
There are a total of 2,919,069 posts in 320,300 threads.
View Active Threads

Who's Online
This forum has 159362 registered members. Please welcome our newest member, AtlKat.
442 Guest(s), 9 Registered Member(s) are currently online.  Details
Woogy, doors12, AJMan, magoo2, Toiletprincess, Lynnwood, Saipan Paradise, Adagio, ddyss