I hope that before you make changes to the maintenance drug, that you're sure the 6mp isn't working. I've heard that even though 6mp and Imuran are pretty much the same, some have done well on Imuran after not taking to 6mp.
I have a co-worker who's daughter is on Methyltrexate. She has Colitis, but it seems to be working for her with no problems.
I'll mention the "web pal" idea to Holly. I'll bet she would really like that. She doesn't discuss her Crohn's with anyone. They even brought up Crohn's as a discussion topic in her Grade 11 health class, and she didn't say a word. It was hard because their were all kinds of misconceptions and myths circulating around the class.
Hollys pretty shy at heart, but she might warm up to it. She would never go on a Teen Crohn's site. She does like Facebood though. Is Marie on that?
Once again, I really hope you get things back on track. I'm sure once you get the meds sorted out, she'll be thriving.