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Regular Member

Date Joined Dec 2009
Total Posts : 65
   Posted 1/30/2010 1:31 PM (GMT -7)   
I'm not actually in a flare atm.  i've been feeling more or less ok for a few weeks as my azathioprine seems to have kicked in (other than last weekend, when i over did it on the alcohol!)
i was just wondering how you guys manage with the fatigue?!  I started a new placement at uni this week, and it has been hard-work and kindof intense.  Since about wed, i've been extremely tired.  i'm hoping that this is just due to the intense new placement, and not the start of a relapse, or a sign of anaemia etc.  The past 3 days, i've needed a nap in the afternoon - each being at least 2 hours! Today i haven't made it out of the house, i've barely made it out of my bed!  Any ideas on how to make it through the rest of my placement?  I can't have caffeine, and i'm getting as much sleep as i possibly can, but it's meaning that i'm getting behind with my work too, and i'm only a week in.... :(

Elite Member

Date Joined Jan 2010
Total Posts : 10094
   Posted 1/30/2010 6:29 PM (GMT -7)   
It's possible the azathioprine is causing the fatigue, particularly if you are on 100mg or higher. I'd talk to your doctor about it.

More likely, though, is that you weren't in full remission and an intensive, stressful placement has tipped your body over the edge into tiredness. I wish I could help, but I can't really. I find that the less I eat, the less my body is stressed by food and more energy I have - but obviously I need to eat to live so it's a catch-22. Enough sleep is vital, so don't feel guilty about taking a nap if you need one. Get tested for anaemia. And good luck: hope the fatigue passes.

Veteran Member

Date Joined Mar 2009
Total Posts : 1118
   Posted 1/31/2010 3:57 AM (GMT -7)   
Hi Do you get B12 shots? these could help. Bev x
Diagnosed with crohns at 13 now 43
Reversal of temp stoma Postponed till ???????
Meds: Iron syrup,Loperimide,Folic acid & Citalopram 60mg (for Anxiety.)

" I may not be there yet, but I'm closer than I was yesterday."

Regular Member

Date Joined Dec 2009
Total Posts : 65
   Posted 1/31/2010 6:00 AM (GMT -7)   
i am on 100mg azathioprine, and i'm due to go up to 125mg on friday, and so i hope this sorts itself out before then! I'm still having regular blood tests with my azathiprine, and so if this continues, i'll call my doctor and see if they have shown any anaemia, especially before i increase my dosage! I dont have b12 shots, hopefully it hasn't come to that yet! Thanks for your help and advice!

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 1/31/2010 7:17 AM (GMT -7)   
How about trying some sublingual B12? That might help a little. Also are you taking the Imuran in the a.m. or p.m.? If its, in the morning, I would suggest switching to taking it at night. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease & Anxiety/Panic
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined Dec 2009
Total Posts : 681
   Posted 1/31/2010 4:19 PM (GMT -7)   
 Tez25 I've had the extreme fatigue three times now The first 2 due to prednisone and the last just recently caused by a 5-asa called salofalk. I'm now trying asacol to see if I don't get this side effect. FYI as I dropped my dose of salofak the hours I slept dropped as well with only a 2 day delay. Thats how I knew it was the salofalk. Ask your Dr. if you could try the same thing and see what happens. Robsmile

Male, 54 years old with Crohn's since 15 years old, diagnosed at age 46. Terminal ileum resected 2002. 5 months of remission. Crohn's has now been active since early 2003. Had a gall bladder removed Nov. of 2009. Currently on Remicade every 8 weeks, Nexium, Iron, B-12 injection every 4 weeks, Morphine Sulfate as needed for pain. Cymbalta for long term pain control. 5-asa Salofalk, Entecort, Imuran and Prednisone in the past.

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