After Humira shot

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New Member

Date Joined Mar 2005
Total Posts : 16
   Posted 2/9/2010 2:23 PM (GMT -7)   
Hi all,
I have had Crohn's for almost 11 years now.  No surgery yet, but in and out of the hospital earlier in the diagnosis. Horrible night sweats every night, failed Remicaide.  I have been on Humira for 2 years now and sometimes the day after my injection I fell like yuck.  In yuck I mean no energy, little nausea, loss of appetite, loss of interest and extreme fatigue.  Has anyone else felt like this the day after your Humira injection?

diagnosed Crohn's disease January 1999 age 22.
currently on:Humira, prednisone, Asacol

Veteran Member

Date Joined Oct 2008
Total Posts : 1343
   Posted 2/9/2010 7:52 PM (GMT -7)   
I used to have a worsening of fatigue the day or two after my shot. That was my only symptom though.
34 years old, Crohn's disease for 15 of them
Resection of ileocecal valve on 09/22/09
Current Meds: LDN, Pentasa, Effexor XR, Zyrtec
Supplements: 3 kinds of Fish Oil, Multi-Vitamin, Vitamin D, Calcium, Magnesium, Coconut Oil, Garlic Oil, CoQ10, Enzymes
SCD since 12/01/08 - eating Stage 3 foods

Regular Member

Date Joined Nov 2008
Total Posts : 63
   Posted 2/10/2010 8:20 AM (GMT -7)   
I failed Remicade tooo.... which I didn't know was possible until my Doctor decided to enlighten me. I'm on Humira now.. I don't really get any of those side effects from it... but has anyone else noticed that it hurts more and more each time you inject? Maybe its just me...
-Heather, 24 yrs. old

- Crohns disease since 1995, officially diagnosed in 2003.

- Bowel resection in Dec. 07, Crohns reoccurred July 08.

- Medications - Entocort 9mg, Humira, Pentasa 2000mg, Bentyl 20 mg, Lexapro 20mg, Wellbutrin SR 150mg, Trazadone 25mg

Regular Member

Date Joined Dec 2008
Total Posts : 75
   Posted 2/11/2010 10:29 AM (GMT -7)   
Yes I get pretty fatigued after my shot as well. The one symptom that really bothers me though is the headaches. They last sometimes up to 4 days after my shot. I hate it. No advil takes it away.
27 yo Female, Crohn's, stricturing type- terminal illeum.
symptoms at age 2....Diagnosed at 6
Bal-resection 1998
Have tried it ALL Currently on Humira, Fish Oil, D3, Entocort, B-12 shots, Align, Multi

Regular Member

Date Joined Aug 2005
Total Posts : 32
   Posted 2/11/2010 6:57 PM (GMT -7)   
Same with me.  Tired, some joint pain and overall kinda achey.  It's usually about 2-3 days after the injection.  It seems to fade quickly though. 

Regular Member

Date Joined Aug 2007
Total Posts : 55
   Posted 2/18/2010 3:54 PM (GMT -7)   
I was on Humira for 1yr 1/2 before it stopped working for me. Had night sweats,so bad that I kept a towel under my pillow to wipe off the sweat. Had bad sinus problems, and fatigue.
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