Has anyone noticed a change in bm timing after stopping Canasa?

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Regular Member

Date Joined Apr 2009
Total Posts : 71
   Posted 2/22/2010 7:59 PM (GMT -7)   
I've been on Canasa now for about 7 months.  The Canasa has worked well for me and I pretty much know the times of the day that I'll need to go to the bathroom.  Over the last few months I've missed a dose here or there (I've fallen asleep before I've had a chance to take it).  What has me concerned is that when I've missed a dose, the next day my BMs are delayed -- when I take it I have 2 BMs within the first two hours of waking up....when I've missed a dose I might not have a BM until 3 or 4 pm (which was actually my old normal before I had any stomach issues).  Since in many regards it's a positive change, I keep telling myself I shouldn't be concerned but I can't help but wonder if somehow my body has become dependent on the Canasa (it doesn't make sense, since I believe Canasa is just mesalamine, but the thought keeps crossing my mind).  Since I've only missed one dose at a time, I'm not sure what would happen on the 2nd day without taking it.  I'm not scheduled to see my doctor for another 2 or 3 months and hadn't put the pieces together last time I saw her, but will ask about it on my next visit.  In the meantime, has anyone else has noticed a similar pattern?

34 - Diagnosed with Crohn's in Nov. '05
Current Meds: Apriso, Canasa, Methotrexate, Pamine Forte, Aciphex, Domperidone, Folic Acid, Restasis, Plaquenil, Doxepin, Xyzal, Zyrtec, Zantac, VSL#3, Calcium, Vitamin D, Centrum, Digestive Enzymes, Thera-tears Omega 3 Supplement, Co-Enzyme Q10
Gluten free since Aug. '03

Regular Member

Date Joined May 2009
Total Posts : 173
   Posted 2/23/2010 9:49 AM (GMT -7)   
I have completely stopped canasa after using them for about 2 years. Things have improved with the stoppage - much better BMs, better frequency, etc. I personally think I developed a mild reaction to the 5-asa meds, so I've stopped colozal as well. Everything is better right now without taking it. I go 1 to 2x a day now. No mucous, but I still see some blood (though very little) at times. I can't complain.
"What can't be changed must be endured" - unknown

DX with distal Crohn's colitis Oct 2007, predominantly in rectum
Colozal (750mg): 3 pills 3xdaily
Cortifoam - 1 nightly
6MP - currently at 100mg and waiting for response......

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