IV cyclosporine or fibrin glue for treatment of fistula

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Regular Member

Date Joined Dec 2008
Total Posts : 24
   Posted 3/14/2010 3:11 PM (GMT -7)   
Has anyone tried either of these? I have a rectovaginal fistula, and my doctor has told me about IV cyclosporine, which requires a 5-7 day hospital stay, and has a 50 percent success rate. I've been taking Humira since May 09, and just added 6MP in January, but it takes 3 months to start working. I've had bad reactions to Flagyl and Cipro, so I won't be taking those again. I've also been thru Remicade and Cimzia, before Humira.

A surgeon has suggested Fibrin glue as a method to fill in the fistula, but I don't know much about it - whether it's temporary or permanent, how successful it is.

I would appreciate stories of anyone's experiences, or other information they may have. Thanks!

44 years old
Crohn's Disease 11 years, diagnosed as ulcerative colitis for 10 years previous to that
Emergency right hemicolectomy & appendectomy Feb 2007
SCD diet on & off for 7 years, restarted strict SCD 1 week ago
(read on HealingWell about people's success healing fistulas with SCD - encouraging!)
Humira & 6MP

exit 4
Regular Member

Date Joined Apr 2009
Total Posts : 148
   Posted 3/14/2010 5:14 PM (GMT -7)   
i had a plug put in that did not work - caused infection and had to be taken out, i was then put on strong antibiotics for the infection that caused c-diff.-lost 40 lbs. flagyl was used to treat c-diff - bad reaction to flagyl. had fistulaomy in october 09 - still recovering from it - wound heal is only about 85%. Hope you have better luck with Fibrin glue.
Male, 45; UC 15 years, Lexapro helped with stress and UC.

Regular Member

Date Joined Dec 2008
Total Posts : 24
   Posted 3/16/2010 11:08 AM (GMT -7)   
exit 4,

Thanks for your reply. Sorry to hear about your bad experience. Be well!


Veteran Member

Date Joined Jan 2003
Total Posts : 6130
   Posted 3/16/2010 6:16 PM (GMT -7)   
had the glue tried a couple times, for my abdominal fistula , but it had too much pressure and wetness and did not stick and blew out. but worth a try i think.


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