Mycobacterium paratuberculosis

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New Member

Date Joined Nov 2009
Total Posts : 19
   Posted 3/23/2010 6:58 PM (GMT -7)   
I can't seem to find any updates on the research of Mycobacterium Paratuberculosis (MAP). Here is the site pertaining to the material of which I speak.
The last update given is from 2004...there MUST be new developments in the timeframe of 6 YEARS! If anyone knows ANYTHING about the progress of this research, or knows where to find articles please inform me. I believe this to be an important finding.
There are a series of medications out know that can be substituted for Azathioprine and other medications to try and fight this powerful bacteria found in dairy and meat. Okay...I just found an article from 2006 stating that the leader in research (Dr. Borody) was to release information about the results of his 20 year project...this is very promising...take a look...
So, I may be getting carried away, and if so tell me- and why. Clarithromycin, Rifabutin, and Clofazimine. These three drugs together are being administered for severe cases, and out of a study of 50 of his own patients, Dr. Borody's treatment left 65% of them in FULL REMISSION. I suppose you first have to be tested first for the bacterium, but it would be worth it. I'm hoping that by now the prices for the meds have gone down signifigantly. Many doctors do not know about this treatment or are bent on keeping things the way they are (resistant to change).
Another find...stating the exact opposite...from 2007- says that there is no basis to support that these three drugs show any signifigant improvement in the disease. =[
Still more research to do however.......
Has anyone tried this fish oil? What are your results? It is suppose to have a nice anti-inflammatory effect.

Post Edited (KevinkHz) : 3/23/2010 8:26:21 PM (GMT-6)

New Member

Date Joined Nov 2009
Total Posts : 19
   Posted 3/24/2010 7:52 AM (GMT -7)   
I don't understand this...If 65% experienced full remission, then how would one come to the conclusion that it was unbenificial?

Becoming undone
Veteran Member

Date Joined Jul 2007
Total Posts : 927
   Posted 3/27/2010 7:27 PM (GMT -7)   
just my 2 cents...but a study has to have reproducible may be that study A showed this, but if study B and C , if conducted in the same manner, did not, there was a problem with study A.
"The earth laughs in flowers"

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Date Joined Sep 2005
Total Posts : 517
   Posted 3/27/2010 8:56 PM (GMT -7)   
the mechanisms of these antibiotic types of drugs are not really entirely known. If you start a bit simpler, such as with neomycin (such as from well known OTC neosporin having neomycin) and it doesnt help... then you can see that there are quite a few other aminoglycosides, in this line of antibiotics. A drug such as Clarithromycin, (of one of 3 of the anti-MAP regimen) is a synthetic, and of similaritys to this Streptomyces line. And you can see that wiki indicates that they can be protein synthesis inhibitors, and seems will thus influence that area (of proofreading, see wiki) but mainly, perhaps, for its benefit in affecting gram negative bacteria. The similar reasoning here, is, as for the probiotics.
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