I was wondering if anyone knew whether or not using two TNF-alpha blockers simultaneously was ever explored as a possibility. Like, if one immunosuppressant alone (or along with other kinds of immunosuppressants) didn’t cover all of your autoimmune issues and you took another TNF-alpha blocker to cover the remaining problems.
I started thinking about
this because I have had uveitis for a few years and I am currently struggling toward an ankylosing spondylitis diagnosis. I have been on Humira, Cimzia and Remicade while dealing with uveitis, none of which has been able to completely control it (though right now, Remicade and 6-MP seem to be keeping it at least manageable). Also, I have been having chronic back pain and stiffness for a while, which my doctors are going back and forth on as far as AS goes. I know that biologics like Enbrel and Simponi are approved for AS, but not for Crohn’s.
I’m rambling a little bit, but I guess my question is if someone has multiple autoimmune disorders (like Crohn’s and RA or AS or uveitis or psoriasis) that weren’t all controlled with one medication alone, do you think it would be possible to be on two at the same time? I realize insurance would likely not cover it, but I’m curious nonetheless.
22 years old, Female.
Diagnosed with Crohn's Ileocolitis November 2008.
Currently taking Remicade, 50 mg 6-MP.