My daughter had a routine appt. today with her (new) GI. Long story short, she's recommending getting off Pentasa altogether, and after a Metabolite test, increasing her Imuran by 25mgs.
She has been doing well for sometime now, which I know is not necessarily and exact science for the future. I felt uncomfortable tampering with her current formula, so she agreed to leave things status quo for now, and re-assess in 4 months.
She does admit to some evidence of Pentasa and Imuran working well synergistically, but in general does not feel Pentasa is a worthwhile drug.
The Imuran is only slighty under the optimum theraputic level, so is likely still effective at the current dosage.
Does anyone have an opinion, or advise on this?