What is the best way to take Pentaza?

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Date Joined Jan 2006
Total Posts : 117
   Posted 4/8/2010 8:54 PM (GMT -7)   
I have inflammation at the beginning of the small intestines. Would it make more sense to take it on an empty stomach without food to make sure it dissolves and attacks the area needed?

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Date Joined Dec 2005
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   Posted 4/8/2010 9:33 PM (GMT -7)   
When I was on Pentasa my GI said it's not as important when or how you take them, just that you get them all down. Don't know if it really matters, but that's what I was told.

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

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Date Joined Jan 2010
Total Posts : 222
   Posted 4/8/2010 10:01 PM (GMT -7)   
I dont take them at meal times specifically, Just in the morning and again at night, but usually the other tablets I take have to be with food, so generally I have had something to eat before I take them anyway.
Michelle 40 years old
Diagnosed with CD 2004 (undiagnosed correctly +- 3 years, wrongly diagnosed with IBS)
Bowel resection 2005
medication: pentasa 500mg , Co-codomol 500mg/32mg codeine
loperamide 2mg (prn - take as many as 10-20 a day)
calcium tablets, multivitamin tablets, Omega 3
Ferrous sulphate(anaemia)
levothyroxine (thyroid)
questran light (3 sachets/day), 3 monthly B12 Injections

Regular Member

Date Joined Sep 2006
Total Posts : 171
   Posted 4/9/2010 12:36 AM (GMT -7)   
vid53, I take Pentasa and I was told that it is designed to dissolve at the end of the small intestine, in the area of the ileum. Perhaps you should bring this up with your GI.

I feel a whole lot more the way I do now than I did a little while ago.
Crohn's Dx April 2006. Pentasa and Entocort EC

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Date Joined May 2003
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   Posted 4/9/2010 5:12 AM (GMT -7)   
I just dig out 16 of my 250 mg Pentasa capsules and put them in a small bowl by my 'puter as I'm in and out of the 'puter room all day and evening. I see them in the the bowl and I take one or two thru out the day. By bedtime I usually only have 1, maybe 2, to take. I take them w/food and I take them w/o food.

The "recommended" or "suggested" dosage is 4 - 250 mg or 2 - 500 mg capsules 4 x a day. The IMPORTANT thing is that you get the full 4 grams of Pentasa down a day. I never take 4 at a time before a meal any more as the 4 capsules plus the water needed to get them down fills me up too much to eat a decent meal.
The Pentasa is in a timed release form so it releases thru the entire length of your small intestine. I can see why you would question taking it before meals given your Crohn's is at the beginning of your small intestine rather than the much more common terminal ileum. I think I'd be inclined to do as you are thinking and take it before meals. But then one wonders if it would remain in the stomach longer if taken WITH food.
Its a good question to ask both your gastro and your family doctor - just to get a couple of different opinions.

My computer says I need to upgrade my brain to be compatible with its new software.

Post Edited (CrohnieToo) : 4/9/2010 6:18:43 AM (GMT-6)

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Date Joined Mar 2007
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   Posted 4/9/2010 12:05 PM (GMT -7)   
I'm pretty sure it does not matter whether you take it with or without food. Just do whatever is convenient for you.

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Date Joined Jan 2006
Total Posts : 117
   Posted 4/9/2010 9:18 PM (GMT -7)   
Thank You for the replies.
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