prednisone-white blood count

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Date Joined Apr 2006
Total Posts : 347
   Posted 4/29/2010 2:26 PM (GMT -7)   
will prednisone cause an elevated white blood count
thanx tigerpawn
mine was 14,000

Regular Member

Date Joined Oct 2008
Total Posts : 377
   Posted 4/29/2010 2:28 PM (GMT -7)   
From what I know of the didn't alter my blood counts, it just sucked up all my calcium and potassium. But I don't know anything more about the stuff.
Allergies and Asthma my whole life: OTC Wal-Zyr D 12-hour
Depression after surgeries and illness of 2003.
Crohns Dx'd: February 2008: Pentasa
Fibromyalgia Dx'd: July 21, 2009: Lyrica, Cymbalta, Hydrocodone, Prenatal Vitamin

Regular Member

Date Joined Mar 2009
Total Posts : 52
   Posted 4/29/2010 9:30 PM (GMT -7)   
Mine went up immediatley after my first injection of solumedrol (IV prednisone). It is very common for this to happen while on corticosteroids. Make sure that you discuss it with your doctor. Steroids do lower the immune system's ability to fight infections so it is important that your doctor knows why you count is up.
25 year old male
college student trying to get his degree in philosophy
Diagnosed Jan. 2008 with Crohns disease.  Been on solumedrol, flagyl, Pentasa, Rowasa, Prednisone, Humira.
Currently on Pentasa and Humira.  Started Humira 4-8-10.

Regular Member

Date Joined Apr 2010
Total Posts : 81
   Posted 4/30/2010 12:33 AM (GMT -7)   
Yes this happens with pred, I always have slightly increased (approx. 12,000) WBC, and when I asked my doctor, he said it's a common thing to happen. 

Regular Member

Date Joined Apr 2009
Total Posts : 384
   Posted 4/30/2010 8:03 AM (GMT -7)   
this happens because prednisone downregulates the adhesion ligands that WBC's use to latch onto blood vessels. as a result, more are in circulation and thus measured on the blood test
Crohn's Colitis diagnosed 6/08
Organic SCD since 4/09
Remicade since 6/09
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Veteran Member

Date Joined Dec 2005
Total Posts : 637
   Posted 4/30/2010 11:31 AM (GMT -7)   
Yes, a higher white count from prednisone is common.

Mine is usually 12-13k on it.(10k is normal max)

If you visit the ER, or see a new doctor, make sure you tell them about this, so they don't go trying to chase down some kind of infection that you don't have.
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