When does Remicaide Stop Working?

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Regular Member

Date Joined Sep 2009
Total Posts : 115
   Posted 4/30/2010 6:34 PM (GMT -7)   
Wondering if any of you have been on Remicaide long term (more than one year) and then had it stop working... I am a worry wart and really hope my husband will have Remicaide work for many years because it has improved his Crohn's so significantly.  Thanks for your input!

Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 4/30/2010 10:25 PM (GMT -7)   
I was on it for 6 & 1/2 years. It stopped working around 6 years. Now I'm on Humira and it's doing ok. Hopefully your hubby with have a good long run with remicade.

Veteran Member

Date Joined May 2009
Total Posts : 506
   Posted 4/30/2010 11:17 PM (GMT -7)   
It all depends on when your body develops antibodies against it.
Diagnosed with CD July 2007
Currently on Remicade, Imuran, probiotics, folic acid, multivitamin.
Resection December 2009

Amor fati - Nietzsche

Regular Member

Date Joined Jul 2009
Total Posts : 61
   Posted 5/3/2010 6:08 AM (GMT -7)   
I was on Remicade for a little over a year and it was great while it lasted. I developed anitbodies and my joints began to hurt. I am making the switch to Humira this month. (hopefully) Try not to worry and enjoy the benefits of Remicade and hope they last. Good luck

Veteran Member

Date Joined Aug 2007
Total Posts : 884
   Posted 5/3/2010 9:28 AM (GMT -7)   
I developed antibodies maybe 6 months in and had to increase the frequency of the dosage.  That maybe helped for a few months and then I could tell it wasn't working very well.  A year in, I started having allergic reactions and stopped taking it. 

Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 

Regular Member

Date Joined Apr 2009
Total Posts : 384
   Posted 5/3/2010 6:19 PM (GMT -7)   
In the SONIC trial update Infliximab, Azathioprine, or Combination Therapy for Crohn’s Disease published recently this year in the NEJM, of the 169 put on infliximab (aka remicade), 59 (39.6%) were in remission at week 50. Not very good results, but hopefully you are in the minority that respond for a long time. Of note, combining infliximab and imuran had 78/169 (46.2%) of patients in remission at week 50. More people will probably be on the combination of drugs due to this trial.
Crohn's Colitis diagnosed 6/08
Organic SCD since 4/09
Remicade since 6/09
Boswellia + Natren's Healthy Trinity probiotic + Cinnamon + Wild Oregano Oil + vitamin D + zinc + Barlean's fish oil

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