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Regular Member

Date Joined Apr 2006
Total Posts : 347
   Posted 5/10/2010 5:24 PM (GMT -7)   
My GI upped my dose of asacol to 2 tablets 4x a day, I would like suggestions on what time of day
u would take each dose.
thanx tigerpawn

Veteran Member

Date Joined Nov 2007
Total Posts : 4384
   Posted 5/10/2010 5:55 PM (GMT -7)   
I take Pentasa and it doesn't seem to matter if I take it with food or not. 4x a day is tough, but I'd suggest first thing in the am and at night before bed. The two other times should be spaced well and when it is convenient for you. Can you set an alarm on your cell phone or computer to remind you? I only have to take my meds twice a might want to ask your doc if you can take a higher dose twice a day instead. I don't know if it is different with Asacol vs. Pentasa.
51 yr. old female, diagnosed with Crohn's in small intestine and terminal ileum Sept-Oct. 2007. Also have IBS, and had Salmonella Dec. '07
currently taking Pentasa- 4 500mg pills per day, Metamucil and colace for constipation, probiotics

Regular Member

Date Joined Jan 2008
Total Posts : 87
   Posted 5/10/2010 5:56 PM (GMT -7)   
I take pentasa four times a day.  I take it at 6 am, noon, 5 pm and 11 pm.

Diagnosed with crohn's in January 2008! 
Pentasa 1000 mg 4 times a day
I am 29 years old and have been married for 4 years.  My husband and I had our baby girl November 16, 2009.  Abigail Christine was 7 pounds 3 ounces and 19 inches long!

Regular Member

Date Joined Apr 2010
Total Posts : 119
   Posted 5/10/2010 6:14 PM (GMT -7)   
I take asacol but I take 4 in the morning and 4 at night which would be the same dose you would be taking (if it is 400 mg tabs). There might be a reason he wants it spaced out like that though so until you can ask him I would set an alarm. I was suppose to take 3 pills 3 times a day but kept forgetting the afternoon dose so thats why he switched me to 4 twice a day (it's not working for me anyway though).

Veteran Member

Date Joined Mar 2007
Total Posts : 1653
   Posted 5/10/2010 6:24 PM (GMT -7)   
Old-school doctors can be strict on telling you to take it 4x/day instead of 2x/day, but research has shown that there is no difference. There is now a movement among GIs to dose it at 2x/day instead of 4x/day because they get better patient compliance.

So take them whenever it's convenient for you. 4 with breakfast, 4 with dinner. Or take 2 with breakfast, 4 with lunch, and 2 with dinner, or 3 with breakfast, 3 with lunch, and 2 with dinner, or, like I said, however you want. And you can even change it from day to day. It doesn't matter, as long as you're taking them.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 5/11/2010 7:08 AM (GMT -7)   
I take Asacol myself. I take 1/2 the daily dose in the morning when I wake up and the other half at bedtime. I kept forgetting the afternoon dose when doing it 3 times a day, and my GI said I could split it into two doses, so I didn't keep forgetting it. Works well that way for me.
Gail*Nanners* Co-Moderator for Crohns Disease 
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*
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