REMICADE vrs. HUMIRA: who's winning?

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Regular Member

Date Joined Sep 2009
Total Posts : 90
   Posted 5/29/2010 1:18 PM (GMT -7)   
So it sounds like there are many of us out there that have been on Remi and have not reached much success.
I am thinking that this is what's happening with me.
And I am wondering why?
It was said at first the REMICADE was "the golden" drug, and it was said to be the best of the best.
It makes me wonder .... I know it is and will continue to work for some people....
but what happens when you let the Remi go and start HUMIRA and then that ends up not working.... then what?
Is Humira better than Remicade? I believe they are in the same class of "SUPER DRUGS".

thoughts, comments... idea
33 yr. old female CANADIAN
dx with UC October 1998
had temp j-pouch: '98-'99
disease free & back to norm: '99-'07
dx. with CD March 2009
Currently taking: Remicade mthly & Imarun

In my next life: I want to be a big beautiful oak tree or something like that... so I can live off of just sunshine and water.

Veteran Member

Date Joined Mar 2005
Total Posts : 1289
   Posted 5/29/2010 3:38 PM (GMT -7)   
i had my 3rd infusion of Remicade last week. it has not helped at all so far. i'm miserable right now...still keeping my fingers crossed.
35 year old male living in AZ.  Diagnosed with Crohns at age of 15.
Currently off Pred.  still taking Asacol.  Just had 1st Remicade infusion a week and a half ago
In the middle of a bad flare now for a year...lost almost 30 lbs. -- gained most of it back now.

Regular Member

Date Joined Jan 2010
Total Posts : 429
   Posted 5/29/2010 3:40 PM (GMT -7)   
I had my 2nd infusion of Remicade on Monday. I think it's helping to close my fistula.
My GI says that there are no studies showing Humira helping to heal fistulas, so let's hope this works!
As for post Remicade plans, I'll deal with it when I have to. Hopefully by then, I won't have a fistula problem.
Diagnosed with typical Crohn's at 16.
Got lucky with Asacol for a year, then even luckier with ten years of relative remission.
Now abscesses and fistulas are having an "atypical" Crohn's party around my junk.
The surgeon said it is inoperable and so I start Remicade on May 7th.

Veteran Member

Date Joined Sep 2006
Total Posts : 845
   Posted 5/30/2010 2:30 AM (GMT -7)   
I have been on Remicade for over 5 years. 4 1/2 concurrent and have returned to it about 8 months now. During my year and half off of Remicade I tried Humira and also cimzia. Humira and Cimzia were very similar as to the success that I had but it failed in comparison to Remicade. All of the medications are golden drugs but Remicade also took away much of the arthritis that I have. None of the drugs have brought me into remission and I pray for a medication that can but Remicade has brought me much relief. I never realized what good it was doing for me until I went off of it and saw how bad I could be. It was terrible and I am very grateful to have a doctor that decided to go against all of the so called rules of Remicade and now being able to go back on it after stopping it.
Now I have said the wonderful things that this medication has done for me but it does not make it better than the other ones. Finding the medication for you is the better medication. Everyone with this disease seems to have different reactions to medications

Veteran Member

Date Joined Jan 2009
Total Posts : 832
   Posted 5/30/2010 10:40 AM (GMT -7)   
My docter offerd me to choose if I like to start Remicade or Humira
I chose Remicade but after 10 months I got allergic reaction at one of the infusions and had to stop.
Then I had to take a 8 week brake until I could start using Humira.

I love Humira.

The nurses always had a hard time finding good veins to use for the Remicade
But with Humira you just stick it in your belly :D
And do all the work yourself.

I had no pain at first from the Humira pens, but it got worse over time so I switched to the syringes and I feel no pain after two shots.
The Humira is a little more fuzz because you have to take care of this expensive drug yourself but its worth it.

Both drugs work well for me.

If I can no longer tolerate Humira there are many drugs available and more on the way. I am not worried
25 year old female from Iceland.
Diagnosed with : Endometriosis march 2007, Anxiety disorder august 2007, CD/UC they don't know witch October 2008, Autoimmune Hepatitis in July 2009
Medication - Humira, Asacol, Librax, Cipralex and Cerazette.

My wonderful dogs :) ~ ~

Veteran Member

Date Joined Dec 2005
Total Posts : 1768
   Posted 5/30/2010 10:31 PM (GMT -7)   
For me, Humira has helped way more than Remicade. I was having obstructions due to strictures at least every 6 months on Remicade, and (knock on wood) have not had once since starting Humira 2 or so years ago!!

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 5/31/2010 7:04 AM (GMT -7)   
I was on remicade for 6+ years. I loved it. It was a miracle drug for me. However, it lost effectiveness and wasn't doing for me what it used to, so I switched to Humira. Been on humira for 2 years and it's ok. It works, but not as well as remicade did. Maybe that's just because I've built up a tolerance to any kind of "biologic" or maybe that's just humira. I don't know. That being said, it works "good enough", so I'll stick with it for now. I have been fortunate not to have problems with strictures or fistulae, so I can't speak about those kinds of issues in correlation with the meds.
Tsitodawg - Tell me about them putting you back on remicade! I want to know more about why your doc did that. I'm wondering if that could be an option for me. Could you email me?

Post Edited (Stef17) : 5/31/2010 8:09:00 AM (GMT-6)

Regular Member

Date Joined Feb 2009
Total Posts : 161
   Posted 5/31/2010 10:01 AM (GMT -7)   
I've been on Remicade for a year and it has been a miracle for me. I have a friend with RA who has been taking it for about 10 years for that with great results. I'm hoping that it will continue to work for me for at least that long!

Becoming undone
Veteran Member

Date Joined Jul 2007
Total Posts : 927
   Posted 5/31/2010 2:48 PM (GMT -7)   
Sofee, that question/concern that you had about if both Remicade and then Humira stop working then what...this is what happened to me...Remicade became less effective, switched to Humira, but that did not work at all...I am now on Cimzia...which IS working (though I have to take double the dose)...I know that it is scary...but there are new drugs being developed...I think the pharmaceutical market has found that autoimmune meds are quite worth their while...

I do have to say, at least for me, Remicade was the BEST for my joint issues...Cimzia seems more effective for my crohn's issues...
"The earth laughs in flowers"

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