I had the same problem, began flaring while on the bi-weekly shot, was upped to weekly shot. That worked for awhile and then once again started flaring. Then I was moved up to two shots a week and methotrexate. I did a 12 week course of methotrexate, every 4 weeks my dose went down and instead of continuing at 10mg per week I stopped taking it and just kept doing the two shots of humira a week. Been doing that for about
9 months. I would talk to your doctor if you are worried that it is not as effective as before. He can check you out and determine the best course of action and then you can discuss those options with him. To answer you initial question, I listened to what my doctor recommended after I told him what was going on and then determined I agrred with his aggressive course of action. As a FYI what triggered me to see him was the concern it had spread to my throat, which it did. I wish you luck and longer lasting relief soon!
Diagnosed Sept. 2004 (two weeks before my wedding)
Currently on 80mg Humira, Prevacid, Methotrexate 25mg and Folic Acid
Have also taken Entocort, Remicade, Pentasa and Imuran