sr5599, you mentioned vedolizumab. The hospital I work near currently has a clinical trial going for it. I looked into it and to qualify, you had to have failed either an immunomodulator (imuran, 6mp) or another biological. There are also other tests they perform to see if you qualify, but you cannot have taken Humira for 30 days before starting it or Cimzia for 60 days. They wouldn't even test me to see if I qualify until I'd been off of Cimzia for 5 weeks and, if I did qualify, I would have had to wait another 3 weeks to start the meds (and then I could have been randomized to receive the placebo). Anyway, I decided I couldn't be off my meds for that long. Anyway, the dr. for the trial did tell me that it does work like Tsyabri but without the risk of PML. I don't know if this will be any indication of how long it will take to be on the market, but when I did a Phase III trial with them for Cimzia, it was available on the market about
a year after I started the trial. It had already been sent to the FDA for approval when the trial started and I'm not sure where vedolizumab is in that process. So, hopefully it will be approved in the next year or so and will be a good alternative for Tysabri.
Crohn's Disease with Arthritis, Non-Erosive Reflux Disease, Gastritis, Hashimoto's Thyroiditis, Endometriosis, Depression/Anxiety