Ibuprofen - thoughts?

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Regular Member

Date Joined Nov 2009
Total Posts : 205
   Posted 7/25/2010 8:37 PM (GMT -7)   
I read/hear conflicting reports on ibuprofen for people with IBD. On the one hand, I hear it's absolutely out-of-the-question for us, then on the other I read that it can be well-tolerated in some patients but should be used sparingly. Does anyone here take ibuprofen? I just popped my first 2 since diagnosis. I have a severely swollen and aching finger that I think may be broken and acetaminophen is not going to do anything for it.

CD diagnosed in 2007
Spent a whole year wondering why no drugs worked for me, only to find out it was probably c-diff (which didn't show up with the regular tests) the entire time. Now I'm retrying all the meds and finding success!
Started Imuran in June 2010

Veteran Member

Date Joined May 2009
Total Posts : 506
   Posted 7/25/2010 8:44 PM (GMT -7)   
The only time I ever take an NSAID is when I have a bad migraine. OTC migraine pills work great.
Diagnosed with CD July 2007
Currently on Remicade, Imuran, probiotics, folic acid, multivitamin.
Resection December 2009

Amor fati - Nietzsche

Veteran Member

Date Joined Mar 2005
Total Posts : 1289
   Posted 7/25/2010 9:13 PM (GMT -7)   
i will not take it at all--not a chance...i've had dome kidney stones and they've given me toradol or something like that in the ER along with morphine...the toradol is basically super strong ibuprophen...works great for the stones but i bled after...seems like the last one helped "kick off" a flare after things had been calming down...just be careful bit i'm sure ibuprophen affects everyone differently.
36 year old male living in AZ.  Diagnosed with Crohns at age of 15.
Currently on 30 mg prednisone.  still taking Asacol.  Just had 3rd Remicade infusion 3 weeks ago
In the middle of a bad flare now for over a year...lost almost 30 lbs. -- gained most of it back now.

stella my labradoodle
New Member

Date Joined Jun 2010
Total Posts : 9
   Posted 7/26/2010 12:00 AM (GMT -7)   
When I last took ibuprophen, it gave me rectal bleeding so I switched to tylenol. You could ask for a presciption for something stonger.
Chohn's diagnosed at age 41 in June 2010. On prednisone, balsalazide, imuran, mulitvitamin, fish oil.

Regular Member

Date Joined Jun 2010
Total Posts : 113
   Posted 7/26/2010 3:59 AM (GMT -7)   
I have been told not to take it.

Regular Member

Date Joined Jul 2008
Total Posts : 384
   Posted 7/26/2010 9:59 AM (GMT -7)   
I have also been told not to take it, but I admit to using it occasionally for a bad headache or muscle aches that I can't deal with any more. Tylenol does absolutely nothing for me and trust me, I've tried. I have no issues with bleeding, so I feel safe taking it occasionally, but the dr told me it can cause us crohnies to flare. I had a pain management doc tell me that if I was going to take it, use the softgel type. It releases quicker and does less damage.

Dx'd w/ Crohn's in 1979 at age 13. Bad flare 2008 but no health insurance so I dealt with it. Colonoscopy in July 2009 caused a perforated colon, emergency bowel resection. 2 fistula's, perianal and perivaginal.

Humira, probiotic, a multivitamin, calcium, magnesium, zinc, and fish oil. I also take Tramadol 50 mg and Klonopin (for anxiety) as needed.

Life may not be the party we hoped for, but while we are here we might as well dance!

Veteran Member

Date Joined Feb 2010
Total Posts : 925
   Posted 7/26/2010 2:25 PM (GMT -7)   
I was told never ever to take it ever again never, and get rid of what was in my house. 
Seriously, my GI did say it was a no-no.  He asks me everytime I am in still reporting problems if I have taken anything other than tylenol.
Diagnosed (FINALLY) UC Sept 09/Diagnosis amended 5-3-10 to Crohn's
Taking Pentasa 500mg/8x/day
Entocort 3X/day
Bentyl as needed
1000 mg Vitamin C
Prilosec 1X/day

Veteran Member

Date Joined May 2010
Total Posts : 8384
   Posted 7/26/2010 2:33 PM (GMT -7)   
I take it sparingly. For a nasty headache, for an acute injury, I'll take it for 24 hours, no more. I've had the pain when going longer than that and I don't want that pain again. But it is extremely effective for inflamed joints, muscle injuries and headaches!

Veteran Member

Date Joined Dec 2005
Total Posts : 1768
   Posted 7/26/2010 4:34 PM (GMT -7)   
I take it occasionally, but usually just one dose when I can't get rid of a headache any other ways (like taking a shower, drinking gatorade, napping etc.)

I've never had bleeding problems though, so that may be why my GI is ok with me taking it every once in a while.

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

Veteran Member

Date Joined Oct 2004
Total Posts : 3932
   Posted 7/26/2010 4:39 PM (GMT -7)   
I sometimes ( like now with active arthritic symptoms) take Advil PM.


Regular Member

Date Joined May 2010
Total Posts : 266
   Posted 7/26/2010 7:43 PM (GMT -7)   
Hi, my GI knows I take prescription anti-inflammatories although IBD diagnosis is recent.  Have attempted to minimize my use as much as possible and have taken my twice a day prescription dose down to once a day and am enduring more pain and or using other products.  I do still take occassional Advil PM's but mostly try to manage the sleep with Tylenol PM (its advail or tylenol with benadryl but for me have more of a Tylenol PM hangover until 10 am -means I'm grumpy . . .)

Meds: Celebrex, Omeprazole, Liadla, Entocort EC 9mg/day, Vit D, Mulitvit, Omega 3's, Ambian, Neurontin.

Regular Member

Date Joined Jan 2010
Total Posts : 257
   Posted 7/26/2010 9:29 PM (GMT -7)   
I think ibuprofen is what led to my initial diagnosis (I ended up with a major GI bleed and in emerg). I have taken it throughout the years for menstrual cramps because it is the only thing that could help me manage that pain. I have just recently gotten an IUD in hopes that the cramps etc will reduce so that I don't have to take any ibuprofen. When I have taken it I really feel it sets things off in my guts (including bleeding). Also, the pharmacist told me that I REALLY shouldn't be taking it now that I am on so much Pentasa (9 per day) because since Pentasa is an aspirin if you combine it with ibuprofen and have a bleed in your intestine the two together could cause a MAJOR bleed. For me, I should avoid it, but I haven't always "behaved"!

Veteran Member

Date Joined Mar 2005
Total Posts : 1289
   Posted 7/26/2010 10:48 PM (GMT -7)   
bottom line sounds like ----- steer clear!
36 year old male living in AZ.  Diagnosed with Crohns at age of 15.
Currently on 30 mg prednisone.  still taking Asacol.  Just had 3rd Remicade infusion 3 weeks ago
In the middle of a bad flare now for over a year...lost almost 30 lbs. -- gained most of it back now.

Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 7/27/2010 8:19 AM (GMT -7)   
I take it all the time. Doesn't bother me a bit and it's the only thing that actually helps the pain. I mostly take it when I have rectal pain from a bad bm. If it's messing with my guts, I haven't noticed.

Veteran Member

Date Joined Apr 2006
Total Posts : 1885
   Posted 7/27/2010 8:22 AM (GMT -7)   
We have been told to absolutely not use it...stay away from it. It isn't worth the risk.
Daughter (22) Dx'd Crohn's 3/06. Misdiagnosed for two years, including by top pediatric Crohn's specialist as stress. No symptoms for the past three years. March '09 colonoscopy showed stricture gone but two spots of inflammation in TI. Used LDN to taper off Entocort last fall. (Was on Entocort since April 06.) Never had D. 4.5 mg LDN, SCD multivit, homemade yogurt, 2000IU vit D3, 1000 mg calcium, 27-54 mg iron, monthly B12 shots, daily oral B12 twice a day (one B complex, then later one B 500), 10mg zinc. SCD diet. 

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 7/27/2010 8:29 AM (GMT -7)   
I think Ibruprofen is what ended my nearly 20 year remission. I would avoid it at all costs. JMHO
Gail*Nanners* Co-Moderator for Crohns Disease 
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined Apr 2006
Total Posts : 1885
   Posted 7/27/2010 9:13 AM (GMT -7)   
Btw, my daughter is the kind of person who refused to take Tylenol, even in high school, and even if she had a truly evil headache. However, in college, she hurt her knee and the doc prescribed a high dose of ibuprofen. She took it for only one or two days and not long after, she landed in the ER with her first-ever full-on flare.   
I don't think it caused her Crohn's, but am sure it helped to serve as a tipping point for exacerbating the condition.  

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 7/27/2010 9:39 AM (GMT -7)   
I avoid it, except the very, very rare time I take *1* - like every couple of months. I am a bleeder, and I notice a big difference (increase in blood) if I take the NSAIDS. A few years ago I hemorrhaged - lost half my blood. The docs thought it might have been, in part, the Aleve I'd taken that weekend. That was before they told me no Aleve and I had no pain meds yet, so it was the only thing that helped take the edge off the pain.
1 fistula with two tracts, crohn's colitis, limited to large intestine
Compounded budesonide 3mg/daily, Cimzia. Dx Osteoporosis 10/08 started Forteo 1/27/09
Failed every other drug and about to prepare for ostomy surgery... In the process of gathering info and meeting with ET nurses.

Regular Member

Date Joined Nov 2009
Total Posts : 145
   Posted 7/27/2010 4:47 PM (GMT -7)   
Hey blueberry....me too!  I originally went in to my GP because of side pain, and he referred me to the Women's clinic.  They looked at me like I was nuts, said it must be cramps (even though I told them I had NEVER had "female" cramps), and told me to take up to 600 mg Ibuprofin a day to help the pain!  3 years of LIBERAL Ibuprofin use later and....here comes the Crohn's!!! 

http://www.newfoundsun.wordpress.com/  (my blog about this journey I have just started)
Crohn's diagnosed 11/12/09
Cytomel and Levoxyl for thyroid.  Supplements for all else as per my ND.

Veteran Member

Date Joined Oct 2009
Total Posts : 1070
   Posted 7/27/2010 7:31 PM (GMT -7)   
I take some time to time. I haven't noticed a problem but I try to avoid it anyway as per medical advice.

Regular Member

Date Joined Jul 2010
Total Posts : 32
   Posted 7/28/2010 4:58 AM (GMT -7)   
I avoid Ibuprofen and take Paracetamol (acetaminofen?) for headaches etc.

For joint pain I find a bag of frozen peas is best.
Diagnosed in 2005 after many years of wrong diagnosis (Gastric Migraines, IBS etc). One resection emergency surgery 3 months after diagnosis due to blockage.
Just taking Questran (colestyramine) with cranberry juice daily and the occasional immodiums now (I have them in every bag).

Veteran Member

Date Joined Jan 2007
Total Posts : 656
   Posted 7/28/2010 3:10 PM (GMT -7)   
Ibuprofen was the straw that broke the camel's back and sent me into emergency surgery. I hadn't yet been diagnosed with Crohn's, and I thought I'd had a particularly bad stomach virus--and then thought I'd somehow pulled an abdominal muscle (because of the intense lower left quadrant paint I was experiencing). I went to the gym teacher at the school where I worked and asked her what to do about a pulled abdominal muscle--and she told me to ice it down and take plenty of Ibuprofen. After two or three days, I was immeasurably worse and barely able to walk or move (or sit still), so I went to my family doctor, who suspected acute appendicitis--but had the sense to get an emergency scan before the surgery. So I steer clear of aspirin and ibuprofen at all costs--even though they'd help with my osteoarthritis. I'd rather have aching joints than more abdominal surgery, thanks.

Regular Member

Date Joined Jul 2009
Total Posts : 417
   Posted 7/28/2010 8:18 PM (GMT -7)   
I take it sparingly. Last time I took any was in January when my joints were aching so bad, not even Tylenol or Lortab was taking the edge off, but it didn't give me any bleeding. Before that I hadn't had any since before I was dx with UC, which now that I look back might have started that flare... I've taken a liking to Tylenol, but that's because I couldn't have advil during pregnancy so I switched.
Diagnosed with UC in February 2009.
Diagnosed with Crohn's Colitis December 2009.
Flaring since October 2008
Possible Rheumatoid Arthritis

Medication: Pentasa 6x daily, Imuran 50 mg, multivitamin, Vit B12 1 g, omeprazole. Sulfasalazine

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