Can crohns cause low white blood counts?

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Regular Member

Date Joined Jan 2006
Total Posts : 117
   Posted 7/28/2010 2:24 PM (GMT -7)   
My doctor just told me to see a hematologist because of my low white blood count, is this normal with crohns? I just came off of
prednisone and the pain seems to be coming back and will probably have to go back on it shortly.


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Date Joined Dec 2008
Total Posts : 15261
   Posted 7/28/2010 2:57 PM (GMT -7)   
I thought people usually have high white blood count when inflammation is present. I think I also read that prednisone can cause your white blood count to raise. Maybe yours is low from coming off prednisone? Has it been low for a while or did it drop recently? Do you get frequent bloodwork?
March 2007: Diagnosed with Mild Proctitis - Canasa as needed.
August 2008 - December 2008: FLARE & Anemic - Started Asacol!!
January 2009 - December 2009: REMISSION!! Asacol (9) + Canasa 2x Daily
December 2009 - January 2010: FLARE!! Asacol + Prednisone + Canasa
February 2010 - April 2010: Colazal + Prednisone + Canasa
May 2010 - June 2010: Lialda + Cort Enema + Prednisone : Colonoscopy: Mild / Moderate Active Pancolitis
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Regular Member

Date Joined Jun 2010
Total Posts : 337
   Posted 7/28/2010 2:59 PM (GMT -7)   
I don't think it's normal...only time my WBC was low was when my dose of Imuran was too high. So they adjusted it and then my count went back up.

Are you taking any meds??
Diagnosed 2002 at 18. Remission for about 7 years. Getting back into the swing of things at 26.

75mg Imuran, 750mg Balsalazide 3x day, Tapering Pred (almost done).


Attempting SCD...fingers crossed!

Veteran Member

Date Joined Sep 2006
Total Posts : 2527
   Posted 7/28/2010 5:17 PM (GMT -7)   
I had low White counts while I was on Imuran and Remicade at the same time to the point where they almost did a bone marrow biopsy..luckily in time on its own miraculously it went to a normal level again...I no longer am on either of those meds
Dx with Crohn's 1987, symptoms as early as 1984.
Temp iliostomy February 2007, reversed June 2007, Ovarian cysts, migraines, allergies (incl food allergies) , oral allergy syndrome (diff than true food allergies), Asthma, Gall Bladder removed 1999, Inguenal hernia 1987

Regular Member

Date Joined May 2010
Total Posts : 266
   Posted 7/28/2010 5:32 PM (GMT -7)   
Hi, Don't know as there is as strong of an association between decreased white counts (leukopenia) and crohns. The stronger association is the meds used to treat crohns - especially steroids or immune suppressing drugs. Attached is a link for more information if you are interested.
Meds: Celebrex, Omeprazole, Liadla, Entocort EC 9mg/day, Vit D, Mulitvit, Omega 3's, Ambian, Neurontin.

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