losing effective of Remicade and switching to Humira

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Regular Member

Date Joined Aug 2009
Total Posts : 377
   Posted 8/23/2010 11:32 AM (GMT -7)   
I was on Remicade for a year and it has seemed to have lost it's effectiveness. I haven't developed antibodies, and I am also taking Methotrexate. My GI finally decided to switch to Humira. I'm wondering for those of you who had to switch, because of loss of effectiveness, how long did it take the Humira to kick in?

I was told it can take up to 3 months to show effectiveness, which isn't very encouraging considering I'm in a flare. I had my loading dose last week and my symptoms still got worse so I requested I be put on Prednisone. That's how I know it's bad!

Anyone want to share their experiences?


Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 8/23/2010 11:42 AM (GMT -7)   
I was on remicade for 6 & 1/2 years - the last 9 months of which remi had lost it's effectiveness, but I was too dumb to figure it out. I switched to Humira 2 years ago and I can honestly say that it hasn't done very much to help me. Sorry to be the bearer of bad news, but I think Humira sucks. It barely holds me and I just recently switched to taking it weekly instead of bi-weekly. I think I probably should have been taking it weekly all along. If you are also taking methotrexate then you might have better results. I hope someone else comes along with better news than mine, but so far... I haven't seen much help. It's better for me to take it than not take it, but it doesn't do what I had hoped it would do.
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