I loved Remicade. It gave me my life back, healed my fistulas, and I was absolutely 100% symptom free for 2 years. But all good things have to come to an end, I suppose, because I developed antibodies to it and we had to stop.
Remicade has been around awhile. I was on it when first diagnosed, I guess it's been 7 years or so ago? And there were people on it before that. It's newish but not brand new so some longer term side effects have been reported. I had no issues, until I built the antibodies to it, and the vast majority of people don't either. The risks of any drug are scary - even things like Tylenol and Benadryl - but sometimes the risk is better than the life we are currently leading.
I was under 3 different GIs care while on it; two had it done in office and one had it done in the outpatient area of the local hospital.