Were you running a fever? Even if you've run a fever before you may have been running a fever longer or higher than other times. You may have been running a low grade fever for far too long and this time was the straw that broke the camel's back.
Each time you had multiple bathroom trips before may have left you a little more depleted of potassium or whatever until this time was the straw that broke the camel's back.
My computer says I need to upgrade my brain to be compatible with its new software.