Friday, was my second oral methotrexate dose. I take 2.5 mg/ 8hrs (7.5 mg/day). I think this is a very low dose but my stomach doesn't like it. The first dose went on fine but with some nasty fatigue that lasted till day 3. This time, things changed. I took an 8mg Zofran injection to combat nausea and vomiting. The next day, nausea and vomiting recurred, so I took another injection. Now, it's the beginning of day 3 and I can't sleep because of nausea, reflux and excessive saliva. I've had GERD and gastritis for more than 13 years now. Is this nausea normal? How long does it last? Till the next dose? I'm supposed to up the dose to 15 mg. Will I be able to make it?
Current meds: Pred (tapered to 7.5 mg - faliure of tapering is the reason for taking methotrexate, Pentasa tablets 2 g, Pentasa Enema, Nexuim 80 mg, mutivitamins.