My husband is a veterinarian and he clipped the following article out of Veterinary
Practice News, May 2012. I don't know if it has already been posted but thought it
was very interesting:
An international group of scientists is testing a live-culture paratuberculosis vaccine for use
To create the vaccine, researchers altered the DNA of Mycobacterium avium subspecies
paratuberculosis (MAP), the causative agent for paratuberculosis, also known as Johne's
disease, in ruminants.
The bacterium has also shown up in the gut of some humans suffering from Crohn's disease,
leading scientists like William Davis, Ph.D., a professor at Washington State University's
Department of Veterinary Medicine and co-developer of the new vaccine, to believe human
intake of MAPs through the food chain may be a cause of Crohn's disease.
Whether MAPs are responsible for Crohn's disease is a hot-button issue, in part because not all
humans who are infected with MAPs develop Crohn's, which affects humans similarly to how
paratuberculosis affects cattle.
"There's really a need to look in greater depth at how paratuberculosis causes disease in
cattle," said Dr. Davis.
The vaccine developed by Davis and his colleagues stimulated an autoimmune response in a
three-month trial with goats, leading to a dramatic reduction in the number of MAPs found
in the subjects during necropsy when compared to a control group. A similar trial with
calves is under way, with necropsies slated for summer.
Post Edited (maggiemay) : 4/27/2012 2:39:59 PM (GMT-6)