So, after 6 months thinking the Remicade was working for me, it turns out that as quickly as 3 weeks after an infusion, the Remicade was not detectable in my blood. And I developed antibodies, so now I need to switch. My main clue was that I got HORRID joint pain & swelling. I mean, it felt as though my joints were sprained or dislocated. I am 37 and was barely able to shuffle around with a cane or dress myself. They started me on MTX last week and prednisone but now they are trying to figure out if I should switch to Humira or Cimza....I go in next week to discuss the next steps. Have any of you had this happen? What did your Dr.s do????