Flagyl can be a miracle drug for my SIBO. I have a high grade partial obstruction at my old resection site and my gut tends to work slowly to begin w/even BC (before Crohn's). Unlike many crohnies, this DD (darned disease) hasn't sped up my gut motility, I still tend to constipation and/or BMs every 3-4 days rather than daily or every other day.
So, yep. I encounter SIBO fairly often. Often enough that for a while I was put on alternating antibiotics the first 10 days of every month for about a year or somewhat better. Flagyl worked best, like virtually overnight - but I could only take half doses, full dose gave me somewhat intense peripheral neuropathy. So, the alternating first 10 days of the month regimen had to be instituted instead. *sigh*
We used tetracyclne and amoxicillin as the alternates. They worked, just not as quickly nor as effectively as good ole Flagyl.
Including a good probiotic, and being concientious about the timing of taking the probiotic and the antibiotic, was the key that finallly broke the cycle when I couldn't "do" the Flagyl anymore and had to do the alternate antibiotic route instead.
There should be 2 hours before, 4 hours after or vice versa; 4 hours before or 2 hours after, between taking the Flagyl or antibiotic and taking the probiotic. I forget which.
My computer says I need to upgrade my brain to be compatible with its new software.