Posted 7/22/2014 10:31 PM (GMT -6)
I was on Humira within months of being diagnosed with Crohn's.
At first it was ok. I would come and go from taking Humira as I would go into remission and would be fine for months on end.
Then eventually I started noticing roving, swollen lumps, first in my fingers, then in my hands, toes, knees, elbows. It kept getting worse and worse until I was missing work from the swelling, couldn't sleep because of the pain in whatever joint was swollen, and couldn't walk on some days.
I really felt like people around me thought I was crazy. My GP gave me T3s and they caused a weird burping symptom that was surprisingly painful in the diaphragm. My GI sent me to a rheumatist, who put me on celebrex while I thought about whether I wanted to try methotrexate. She said I had lupus markers and sent me for more tests. The celebrex didn't do anything.
Finally, my mom said that she'd noticed I had terrible (ruin your whole life in 20 minutes level) mood swings that corresponded to my Humira doses. I stopped taking the humira and the lupus markers, mood swings, and swelling completely disappeared. This all happened over the course of more than a year and led to a job loss. What was maybe most upsetting was that my mom had to figure it out, after two specialists couldn't see it and prescribed more meds to try to fix a major problem caused by the first one.
I still haven't found my magic cocktail, and usually get the moon face/moustache/fatigue/nausea or whatever any given drug threatens. Even so, Humira was the root of the second worst Crohn's story I have. I'm sure I'll get around to telling about the first, eventually.