Posted 5/29/2014 3:26 PM (GMT -6)
Imuran, by a country mile. Entocort is not okay for long-term use.
Prednisolone comes in a far wider range of doses (it comes in 5mg and 1mg pills) than Entocort, so what about switching to a roughly equivalent dose of Pred and then working your way down to 0mg very, very slowly?
You mentioned sun exposure. Yes, Imuran can increase photosensitivity. My arm got badly burned on its sister med, 6MP, once and that was in the UK. *shakes head*. Talk to your doc about that, but I presume sunscreen would still block out the harmful UV rays.
Like Gumby said, the TMPT test is usually used to see if you can safely metabolise the Imuran (a small minority cannot), but you will still need regular blood tests. My liver was fine on it, but my blood cell count got a bashing. Sometimes that's just temporary while your body adjusts to the medication.
Basically, I don't think Imuran is over the top. I would recommend Pentasa, but, honestly, the 5-ASAs are like placebos for Crohn's disease. The dose that you would need to be on is relatively low; transplant patients are typically on 2-3x higher a dose than Crohn's patients. If you suffer from bad nausea at first, try reducing the dose and working your way up as tolerated. I did this and it worked pretty well; was totally over the nausea after 2 weeks.