Posted 10/9/2016 9:57 PM (GMT -8)
It shouldn't be an either/or question of imuran or Humira. If you start Humira, you should start - or already be on - imuran. Studies have shown a clear benefit of taking the two together, both in terms of treating the disease and in terms of preventing antibody formation to the biologic med.
DaleB, what is the status of your Crohn's? Where is it located and how bad is it? Imuran requires blood monitoring and can take a few months to help. If your disease is bad, that might be too long to wait. If your disease isn't appearing to be too aggressive, you may have time to try imuran alone and see how it goes, knowing you can add a biologic later as needed.
Also, for what it's worth, Remicade continues to have the best data for treating IBD, compared to the other biologics.