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Severe Food Poisoning May Be a Cause of Crohn’s Disease

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pb4
Elite Member
Joined : Feb 2004
Posts : 20577
Posted 10/26/2016 10:41 AM (GMT -7)
link from IBD News...


http://ibdnewstoday.com/2016/10/26/severe-food-poisoning-bacteria-possibly-linked-to-crohns-disease-onset[url]

Not sure what's going on, I tried 3 times to get the link to activate the link (as I've done many times before with no issues) but it won't work for me.
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/26/2016 11:50 AM (GMT -7)
Hey pb4, how are you? I hope you're doing good. Thanks for the link.

Here its clickable form:
ibdnewstoday.com/2016/10/26/severe-food-poisoning-bacteria-possibly-linked-to-crohns-disease-onset

Here the actual study link, full text:
journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005907

Here, from another forum member, a list of AIEC studies: www.crohnsforum.com/showthread.php?t=52198

It's pretty good.

Here is the discussion about this article in another forum:
www.crohnsforum.com/showthread.php?t=79244


the study article said...
AIEC strain NRG857c (serotype O83:H1) was isolated from an ileal tissue biopsy from a CD patient in Charite Hospital (Berlin, Germany) and its genome sequence was determined previously [10, 54]. A mutant that is sensitized to the action of host defense peptides by deletion of the genes arlABC (NRG857c ΔPI6) was characterized previously [34].

Post Edited (xy123) : 10/26/2016 1:18:16 PM (GMT-6)

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NickyFurlano
Regular Member
Joined : Apr 2016
Posts : 48
Posted 10/27/2016 1:08 AM (GMT -7)
Exactly the cause of crohn's for me way back in April of 1997. I nearly died from food poisoning.
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pb4
Elite Member
Joined : Feb 2004
Posts : 20577
Posted 10/28/2016 10:27 PM (GMT -7)
Hey there xy123,

Thanks for asking :) I'm doing better, not 100% but I expect it to take some time....I've just started doing gut physiotherapy offered at my university hospital where my GI clinic is located and I think it's gonna make a big difference too (they incorporate meditation to help with constipation while actually on the toilet) along with other things....it's a great program and majorly needed.

I hope you're doing well?

Thanks for the links, just moved so haven't had much time on the computer lately, will definitely check them out soon :)
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/29/2016 1:18 AM (GMT -7)
It's nice to hear you're doing better. I'm doing great (had a colostomy surgery 7 months ago, it's enabled me to live a pain-free and relatively much more healthy life.)

I'm not 100% too, I've stopped aspiring to lead a robustly healthy life with Crohn's some recent years ago, I'm extremely grateful to be like 70-85%, if it is constant... haha :)

I haven't heard gut physiotherapy before, a curious method, looks like it helps.
/www.ncbi.nlm.nih.gov/pmc/articles/PMC4305552/

If the constipation isn't due to a stricture or narrowing, then maybe magnesium citrate helps?

We eat dried apricots in my country to relieve constipation.

wiki article said...
...Due to their high fiber-to-volume ratio, they are sometimes used to relieve constipation or induce diarrhea.

If you're going to buy them, make sure you buy the dark colored ones. They are much better. Don't buy the orange-colored ones, if possible.

the article said...
Dried apricots are a type of traditional dried fruit. When treated with sulfur dioxide (E220), the color is vivid orange.Organic fruit not treated with sulfur vapor is darker in color and has a coarser texture. Generally, the lighter the color, the higher the SO2 content. Light-colored varieties (with the sulfur content of more than 2000 ppm) are banned in the European Union.

/en.wikipedia.org/wiki/Dried_apricot

Well, now I crave them...

Good luck.
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pb4
Elite Member
Joined : Feb 2004
Posts : 20577
Posted 10/29/2016 12:21 PM (GMT -7)

xy123 said...
It's nice to hear you're doing better. I'm doing great (had a colostomy surgery 7 months ago, it's enabled me to live a pain-free and relatively much more healthy life.)

I'm not 100% too, I've stopped aspiring to lead a robustly healthy life with Crohn's some recent years ago, I'm extremely grateful to be like 70-85%, if it is constant... haha :)

I haven't heard gut physiotherapy before, a curious method, looks like it helps.
/www.ncbi.nlm.nih.gov/pmc/articles/PMC4305552/

If the constipation isn't due to a stricture or narrowing, then maybe magnesium citrate helps?

We eat dried apricots in my country to relieve constipation.

wiki article said...
...Due to their high fiber-to-volume ratio, they are sometimes used to relieve constipation or induce diarrhea.

If you're going to buy them, make sure you buy the dark colored ones. They are much better. Don't buy the orange-colored ones, if possible.

the article said...
Dried apricots are a type of traditional dried fruit. When treated with sulfur dioxide (E220), the color is vivid orange.Organic fruit not treated with sulfur vapor is darker in color and has a coarser texture. Generally, the lighter the color, the higher the SO2 content. Light-colored varieties (with the sulfur content of more than 2000 ppm) are banned in the European Union.

/en.wikipedia.org/wiki/Dried_apricot

Well, now I crave them...

Good luck.

Hi xy123,
I'm so happy you're feeling so well yeah

My constipation is due to IBS, I only have a little rectal scaring (from 23 yrs of flaring on and off in the rectum, but constant in the colon with my crohn's, yet my colon looks beautiful since the Humira and MMJ) my GI told me to use Lax a Day everyday, it's the safest OTC for constipation that doesn't cause your bowels to become dependent on it like many other OTC products do, so I'm happy with that and it works better than when I was drinking prune juice.

I've also been also doing meditations daily (and just learned from my gut physiotherapist that there are actual "constipation meditations/toilet meditations" for those that suffer bowel and/or bladder pains and issues and it's definitely helpful since I started doing it on the toilet). The other day I actually had no BM's the entire day without a single urge of any kind, it was amazing and I still was able to pass my BM's the next day so not going for a whole day didn't even cause my constipation to get worse.

Thanks for the tips on the apricots (never really been a fan, drinking the prune juice wasn't my favorite either) especially when it stopped working for my severe constipation....that's when my GI gave me a sample of Lax a day.
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/29/2016 1:27 PM (GMT -7)
about two years ago I read some books and did research on mindfulness meditation for a brief period of time.

Although I found the concept enlightening, I couldn't apply it to my own life, to my own perspective. It is hard to do with our modern, city life. At least I found it hard, but nonetheless, I appreciate the info I gathered from those readings.

Ah, I've changed my way of breathing tho, it was easier. This is how I breathe now:

Abdominal breathing: /en.wikipedia.org/wiki/Diaphragmatic_breathing

wiki article said...

This deep breathing is marked by expansion of the abdomen rather than the chest when breathing. It is a form of complementary and alternative treatment.

Diaphramatic breathing is also known scientifically as eupnea, which is a natural and relaxed form of breathing in all mammals. Eupnea occurs in mammals whenever they are in a state of relaxation, i.e. when there is no clear and present danger in their environment.

***
Although this seems unrelated now, I'd advise you to be careful with MMJ. I found that it can mess with your mind, it can change your personality, your social perception... I haven't used it for the last 4-5 months I think, and I'm grateful for that. But if my pains and uncontrolled inflammation do return, then I would definitely use it again.
Also, it really can make your constipation much much worse. As you know, it slows down intestinal peristalsis. But it sounds you're handling the C well.
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pb4
Elite Member
Joined : Feb 2004
Posts : 20577
Posted 10/30/2016 1:45 AM (GMT -7)
Thanks xy123 :)

I know they say that meditation can be difficult, honestly as long as you can focus, you can learn to meditate simply because, that's all meditation is. It's also best to start with guided meditations, a short 3-5 minutes a day and building up. Meditating/focusing is individual, there's is NO right or wrong, making it individual. You can meditate about anything you want (It's not about clearing one's mind of everything, it's about focusing on a variety of things with positively and relaxation).
There are a variety of meditation exercises, breathing, letting go of thoughts of anything negative that is happening around you and focusing on happy thoughts. The longer you do it, the easier and more natural it becomes....and not only do you get into better touch with your guidance but with others that you interact with as well, it's not only a great coping tool that we all have the natural ability to use to connect with our inner selves/guidance.
Check out this link....

http://www.artofliving.org/meditation-consciousness


There's more, scientific research on meditation which has proven that meditating makes you naturally become more mindful and consciously more aware and actually affect matter... the long time experiments on consciousness that brought scientist to the conclusion that consciousness continues on for all of us indefinitely and meditation affecting matter proves it....
check out this link....

https://www.youtube.com/watch?v=nRSBaq3vAeYVIEW IMAGE" target="_blank">

Meditation physically changes brain cells too....easy google.


As far as the MJ, There's proof that it can actually help with depression (so long as you aren't the type that has a negative emotional effect from it) but MJ was somewhat helpful with my severe depression because I was in a more positive mindset whenever I smoked it) adding antidepressants and then an ADD med with it combined with the MJ as well as meditation relaxing me and doing a variety of practices has boosted my mood quite a bit and it's been getting better daily.

Here's a link about MJ to treat depressions and PSTD....

VIEW IMAGE


Let me know what you think if you're interested, I don't want to push you into anything, just sharing info I've been researching for a long time now (great break from Crohn's and IBS research cuz that was depressing and frustrating) so for me it's no wonder why I'm not feeling suicidal anymore because I've been putting things to the test and finding better results with coping and enjoying life more...I just want to share with anyone else that has struggled for a long time. :-)
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/30/2016 5:37 AM (GMT -7)
Thank you, I'm interested in these topics too. My main problem is attention, concentration; and obsessions lets say.

If I were to use medications like antidepressants, and/or add meds it would be much easier to focus on being mindful, but then again If you are using these meds, then I don't think mindfulness meditation is as needed before.

I'm thinking very low carb, like ketogenic diet to help with my concentration problems. I think it may be beneficial. I also take fish oil for that purpose (concentration).

I used mirtazapine for 14 days after my resection surgery to help me sleep and gain weight. The drug also made my mental problems much better. Helped with concentration a lot, to the point that I couldn't believe it happening. But it has nasty side effects and I'm generally (though not always) an anti psych med kind of a man.

Also, I found out that mirtazapine increases some important cytokines that play central role in Crohn's disease like IL-1B, TNF-a...

"Kast[81] (2003) compared the use of bupropion and mirtazapine in patients with Crohn’s disease. He speculated that both of these antidepressants have the potential to affect inflammatory responses: bupropion by lowering TNFα and mirtazapine by increasing its level. Therefore, according to the hypothesis of Kast[81] (2003), there are theoretical reasons for recommending bupropion and cautioning against mirtazapine when treating depression in patients with Crohn’s disease. Although Kast’s explanations appear logical and are supported by other investigators[82], their practical effectiveness needs to be experimentally confirmed in appropriate clinical studies[55]."
/www.ncbi.nlm.nih.gov/pmc/articles/PMC3974522/

You may benefit from reading these articles if you're using psych meds:

Impact of antidepressants on cytokine production of depressed patients in vitro.

/www.ncbi.nlm.nih.gov/pubmed/24257035

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease
/www.ncbi.nlm.nih.gov/pmc/articles/PMC3974522/

My main problem with psych meds is that we don't really know about their long term effects on brain physiology. We don't have enough data on their possibly permanent effects on brain, even if you stop using them, and also, studies on pharmacological area of psychiatry are highly biased. I also question validity and quality of psychiatry and psychology on the basis of philosophy of science...

But what is the replacement for these suspicious areas, the answer to that, practically at least, on a social level is hard to give. Better nutrition, education, better lives, better social systems... Difficult problems to solve I think.
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/30/2016 11:35 AM (GMT -7)
All this talking about mindfulness, letting go etc... reminds me of tool's magnificent song "The Grudge".

"... Saturn comes back around to show you everything
Let's you choose what you will, will not see and then
Drags you down like a stone or lifts you up again
Spits you out like a child, light and innocent.

Saturn comes back around. Lifts you up like a child
Or drags you down like a stone to
Consume you till you choose to let this go.
Choose to let this go.

Give away the stone. Let the oceans take and
Trans*mutate this cold and fated anchor.
Give away the stone. Let the waters kiss and
Trans*mutate these leaden grudges into gold.
Let go."

/www.youtube.com/watch?v=IQQlyJjBvcE
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pb4
Elite Member
Joined : Feb 2004
Posts : 20577
Posted 10/30/2016 11:53 PM (GMT -7)
YIKES, did my highlighted links ever get messed up lol!!! Well, I see you got the gist of it xy123 :)

No worries about the antidepressants and the ADD meds, I'm on low doses of each and only started the antidepressants (to help with IBS and my depression) early this summer and then the low dose ADD med that actually boosts the Cipralex antidepressants with using the ADD Vyvanse together helping my IBS and my depression started at the end of summer.....it's not long term, 6 months or sooner and I'll be weaning down slowly coming completely off of them....No need to be on any of those types of drugs when you've finally tuned in to meditating since that is what we can use to heal ourselves and I'm sure I don't have to say it again but, scientific research on varying levels, backs it all up.

Love the song by the way :) Have a great night and be well!
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xy123
Veteran Member
Joined : Feb 2014
Posts : 1070
Posted 10/31/2016 5:52 AM (GMT -7)
I agree with you pb4 :) . I wish you an endless remission (or a cure in our life-time?). Good bye for now.
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DaveF
Veteran Member
Joined : Jan 2010
Posts : 1122
Posted 11/3/2016 2:33 PM (GMT -7)
I took anti biotics (tetracycline) for acne as a kid
I lived in Alberta, so presumably I was exposed to Maps
I also had food poisoning twice. One I was in the hospital for a short while as they addressed the nausea, de hydration, ...

I have been diagnosed with Crohn's, ibs, sibo and other stuff. If each of the above contributes I never had a chance.

Maybe I was predisposed by anti biotics, then ate steak, and food poisoning put me in the winners circle. .lucky me
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