There is ongoing research regarding vitamin b12 as well as zinc deficiencies in Crohn's. Both are involved in modulating immune response, so stand very connected to the mechanism of Crohn's.
I would throw every rock I could at a kid however. I'd see a g.i. who researches it and get b12 shots, and ask about
zinc's absorption in your kid's g.i. tract. If they offered it as a shot, that'd be the best approach to intake.
The downside of the anti-tnf-alphas is that they also do not guarantee mucosal healing. If you read any of the studies on them, you will find them uncontrolled and mildly effective (far less so than they are for symptom healing and bloodwork, much like the diet. The mucosa being damaged is resistant). 15-50% of people have some mucosal healing after a year on infliximab or vedolizumab.
Clinical and mucosal improvement with specific carbohydrate diet in pediatric Crohn disease.
Did find that it worked for the mucosa in 2/7 participants, using capsule endoscopy. So, rarely it may work. I wouldn't bet on that rate though. I do however find that about
that many people are unable to follow the SCD due to the precision of the guidelines and the complexity of processed foods.
My advice as an adult who researches in human molecular biology and has had Crohn's for eight years: get the kid on entyvio(or some anti-tnf-a) now, and wait until he starts to loose response. In the mean time, set up an alternate plan with a G.I. dealing with modifying the body's own immunology(b12, zinc supplementation.) It'll let you wait a few years until the kid starts loosing response (and has grown for a while with good nutritional absorption) to investigate supplementation in conjunction with the scd.
Post Edited (wibblypig) : 8/15/2018 11:04:36 AM (GMT-6)