I am still on Remicade and Methotrexate. 6 years. No antibodies as long as I take the MX. I have begged to be taken off the MX but GI said no. He thinks you need the dual therapy to ensure you do not build antibodies. I actually shopped my GIs answer with 2 other GIs and they both recommended I stay on dual therapy.
A lady in one of my support groups with Crohns disease stopped taking her MX and continued with her Remicade infusions. Last week she ended up in the hospital due to a reaction during her infusion.
But....if you are younger, haven't had any issues.....you may be able to do it. Another lady in our support group stopped her dual therapy over 10 years ago...and she's still taking Remicade and its working.
So I am unsure.
Has your daughter had any tests to show antibody levels? Is that something they can do to monitor it? I don't know if Imuran will drive antibodies down once you develop them.
I do know that with MX there is a small group of people that it will drive their antibody level to zero even after they have developed antibodies. Its done it for me twice. I had stopped taking it due to surgery and then shingles. This surgery I did not stop it....so I am still at 0.
I wish your daughter good health and good luck. Please keep us updated.
Thanks for the detailed reply Clo,
Her GI didn't recommend any testing for antibodies, which I found sort of odd as well. They did a conference call, and went over her recent blood work. Based on where she's at right now, and her blood work was perfectly normal in every area except iron, which has been a constant problem. I think her decision to stop the Imuran, was based on her age. Didn't want her taking it for years to come. Didn't seem to have that concern with Remicade at all.
Hoping for the best right now. Thanks again, will keep updated.