Humira vs. Remicade

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Regular Member

Date Joined Mar 2007
Total Posts : 388
   Posted 8/16/2007 2:33 PM (GMT -7)   
Hello from the Ulcerative Colitis forum! I was told to cross-post this question here, since some of you might be more familiar.

What's the difference between Remicade and Humira?

Besides the added cost, Humira you inject yourself, I know Remicade is part mouse DNA while Humira is all human. . .

Is Humira safer than Remicade, in the long term? Does it work better? Last longer?

My doctor sounds like he's bigger on Humira than Remicade, I just wanted some info before I asked him why.
12 Asacol
100 mg Imuran
6 or 9 fish oil pills
4 Acidophilus pills
4 Caprylic Acid pills

Regular Member

Date Joined Aug 2007
Total Posts : 349
   Posted 8/16/2007 2:37 PM (GMT -7)   
Im supposed to start HUMIRA in the next month and the biggest benefit from what I can tell is that the time you will you save yourself every other week by giving it to yourself rather than at an infusion station.
Symptoms Of Crohn's June of '06 (21 years old 285lbs). Colonoscopy in Jan '07 no sign of Crohn's. Surgery for a Fistula in April '07, diagnosed suggestive Crohn's in May '07. August '07 small bowel follow through, diagnosed with Crohn's (22 years old 165lbs). Starting HUMIRA 9/10/2007.

Veteran Member

Date Joined Mar 2005
Total Posts : 4305
   Posted 8/16/2007 11:27 PM (GMT -7)   
Hi, Iam on Humira and I will try to answer your questions for you.The differet's between Remicade and HUmira is this.Remicade is like you said made from mice cells and Humira again like you said is human.

With Remicade it had to be adminsterd though an IV and you have to either at a hospital or clinic.Depending how long it takes depends on the person.When I was on remicade it useraly (sp)took about two hours providing that they did not have to stop.When I would go in for a Remicade treatment they would give me benerdryle (SP).

I have been on Humira for a while now and I give my self a shot every other week and the only reaction that I have is it does sting a little when adminstering.I also get a little red around the injection site but it disapers with in a few secounds and please remember every is different.

For me Remicade helped but not liked we had hoped it would and I also built up serum sickness as well so had to come off.I have RA and my Rhuemy is the one that put me on Humira and at the time it was not FDA for crohns yet but it help the old gut.

When I was first put on Humira I was in a wheelchair due to sever Edema and the fact that I have sever RA and OA to boot and nothing and I did help-ed that is untill Humira.After being on Humira for a couple of months I was getting to the point that I could do theraphy in oder to stresnthen my mucels up so I could basicly learn to walk again.

I wish you well and let me know what you choose to do.

Regular Member

Date Joined Mar 2007
Total Posts : 69
   Posted 8/17/2007 5:31 PM (GMT -7)   
I was on remicade between surgeries, and was to sick to notice if it helped or not. I then developed serum sickness- reaction to it. That caused a great deal of pain and more days in the hospital. Now over 7 years later i am on humira. I was scared to death to start, but did not have a reaction as of yet. I did have shingles about 14 weeks into it, but went back on after a month with no problem. My only complaint with humira is the way i usually feel slugish the next day. I usually take it easy the next day, but the achey all over feeling goes away.
When i had the remicade it was fully covered under my insurance. Now with the humira i have a shot every week, and a co-pay of 25$ a month.
My pharmacy delivers it to my door and it has to be stored in the refrigerator.

New Member

Date Joined Aug 2007
Total Posts : 12
   Posted 8/24/2007 5:38 PM (GMT -7)   
I am so glad I finally found something on here about Humira. My doctor wants me to start it next week. After reading the side effects I am worried.
I have UC but the doctor told me Humira was being use for it and that it was approved for crohns. It is so scary and such a hard decision to make.
I know I can not continue with flare ups. I can not take immuran anymore. So it is either remicade of humira. My doctor prefers the Humira.
I received my first presciption ups today and put it in the refigerator. I will go and talk to my doctor next week and decide what to do.
I was diagnosed 2005 with UC.

Aimee =)
Veteran Member

Date Joined Jun 2004
Total Posts : 1020
   Posted 8/24/2007 8:37 PM (GMT -7)   
I have used both, both have worked extremely well for me. Humira is MUCH cheaper for me and MUCH easier since I don't have to take a half day off work to get the infusion. Just less hassle.

I also have absolutely no side effects with Humira and with Remicade I had hair loss. I did eventually build antibodies to Remicade and reacted to it the last 3 infusions so I had to stop using it. From what I understand, there is less likelyhood of building antibodies to Humira.

Veteran Member

Date Joined Dec 2005
Total Posts : 544
   Posted 8/25/2007 6:12 AM (GMT -7)   
It seems to me that Humira is the lesser of two evils.  I have my start up doses in the fridge as of yesterday and will start on them next Friday. 
My gastro wanted me on Remicade over a year ago, but the stuff I read about the possible side effects, the costs and number of folks who were rejecting it because of the rodent DNA kept me off of I have chosen Humira as my next step....I feel there is less chance of rejection...less side effects to worry about and the cost is lower by more than 90%....
dx IBS 1999   UC 2000   CD 2001
Tested BIOGEN TYSABRI (gave me 2 years of remission)
currently on Low Dose Netroxene (started Jan. 19, 2007)...against Dr's wishes, he was pushing for Remicade.  Stopped the Naltrexone July 28th...will start Humira Aug 28th 2006
Crohns is currently active and has been since April of 2005
50 yrs old

New Member

Date Joined Sep 2007
Total Posts : 2
   Posted 9/19/2007 2:04 PM (GMT -7)   
I was diagnosed in February 2005 with RA and have been on Remicade since that time, and have responded very well to the infusions.  I have never had any side effects at all, Remicade made all the difference.  However, starting this week I am switching to Humira, simply because I am tired of the IV treatment, that and cost.  The meds are the same price for me no matter what I'm one because I get them through my mail in program, but the cost of having the infusion and all that entails can be eliminated with self injected shots.  But mostly, just tired of the IV.  I've read all the possible side effects with Humira, and it is a bit scary.  But the possible side effects of Remicade are no less scary, and I did so well on that.  I guess we shall see if I respond as well to the Humira as I've done with the Remicade, because I've heard that there's a possibility I can't go back to the Remicade if the Humira doesn't work as well.   Don't let the "possible" side effects keep you from trying the Remicade, every body is different.  Just because one didn't do well, doesn't mean you won't.  It made an enormous difference in my mobility, pain level, and flair ups became almost none existant.  And when I did have a flair up, they were never as severe as they were before the Remicade.

Post Edited (kickinRA) : 9/19/2007 3:05:44 PM (GMT-6)

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