Humira & my first serious secondary infection

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Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 9/26/2007 10:59 PM (GMT -7)   
Thanks to all the immunosuppresive drugs!  I was in the ER again last night...this morning...what day is it anyway?!  Two impacted wisdom teeth & a failed root canal.  Two weeks after by birthday gallstone present I might add and the constant vaginal bleed from an ovarian cyst.
Good news ovarian cancer!
Anyway...I had taken my Humira pen injection 3 days ago and had just survived the typical flu post injection symptoms..when WHAM, all of a sudden with no prior symptoms...the infection & searing pain hit my mouth and swelled it shut within 3 hours!  So I got to thinking this infection is in my head and I need a dental block for pain and antibiotics ASAP...hence the ER.  I didn't want to wait for a oral surgeon visit, most likely 24 hours later, to start the antibiotics since the Humira was causing the infection to be so aggressive!  The ER doc had never done a dental block, bless his heart and told me not to hold it against him if he missed the nerve.  My response was go for it and not to hold it against me if I decked him in the process!  Inject humor here!  He ended up doing a great job even though the block doesn't last more than 5-6 hours it allowed time for the Rocifin (spelling?) antibiotic injection to start working wonders.
Now, I'll take responsibilty for not following up on the failed root canal for over a year cause I wanted my body to heal from the resection and to be on the lowest possible dose of predinose before doing any further surgery.  Not to keen on all that oral bacteria floating around in my bloodstream post op dental procedure and the fact that I'll have to stop the imuran temporarily and possibly the Humira in preparation for the surgery anyway.  It's another CD flare waiting to happen.
So....just thought I'd share.  I have the oxycotin chatty syndrome tonight and have another hour before taking my follow up antibiotics so you guys are just going to have to put up with my middle of the night blah...blah...blah!  Thanks for being here to listen!
Dx'd Jan'06, 1st Resection 7/06, Predinsone, Humira, Imuran, B12 injections, Nexium. Secondary conditions: Psorasis, Acne, Fatigue, Joint Pain, Lactose Intolerant, gallstones, fibroid cysts, peri-menopausal.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 9/27/2007 7:28 AM (GMT -7)   
Oh great we got us a numb drugged up witch on our hands!!! Broom if its not one thing with you its another. You need to start being a good witch and get well!! Did you at least wake the husband up just cause your up? You know he would have done that if it were him. LOL!
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

Veteran Member

Date Joined Mar 2007
Total Posts : 4527
   Posted 9/27/2007 8:15 AM (GMT -7)   
Hi Sure sounds like you had a not so good night keeping the young lads busy are you? Hope your better. Got myself a doozy cold chest and head so on antiboctics too with my Rem. It is Thurs. now by the way .Went to the dentist Tues for a permanent filling and Wed. running because of my cold .I do have rather a lovely cough. I Do love Nanners sense of humor!Well only wishing the best for you and glad no cancer in the ovaries . Get yourself better soon .lol gail

Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 9/27/2007 7:12 PM (GMT -7)   
Well's getting so close to my favorite time of year I'm considering smashing into that tree and just hanging out there awhile like I do every year this time.

Funny thing, my boss has been going through some tough medical issues lately and one week it's been him and the other week me. Ask him today if this was some kind of weird competition between us and if it was, HE WINS! All this "crap" hasn't let up since early July with me!

I must admit since I don't drink my occasional wine anymore (with the exception of my son's wedding), the numbed up part is pretty good for a change! Can't wait for the anethesia!

The oral surgeon is going in for 2 infected, impacted wisdom teeth and one failed root canal next Wednesday. I started preparing today by uping my probiotics, eating more protein, lowering my sugar/yeast intake even further and uping the vitamin C . Two days after the oral surgery I get to do my next Humira. Hisssss.

Oh, and no I didn't wake the hubby. He heard me coming in at 4am the night of the ER visit so I let him sleep. He also has some nice dental work coming up at the beginning of the month. Sooooooooo, he better be nice to me cause if he's not....I'll surely sew him to the sheets when he's sleep and beat the bejeebies out of him with my broom...heeeheee! (Just Jokin')
Dx'd Jan'06, 1st Resection 7/06, Predinsone, Humira, Imuran, B12 injections, Nexium. Secondary conditions: Psorasis, Acne, Fatigue, Joint Pain, Lactose Intolerant, gallstones, fibroid cysts, peri-menopausal.

Veteran Member

Date Joined Dec 2005
Total Posts : 544
   Posted 9/28/2007 6:07 AM (GMT -7)   

Broomhilda...sorry to but in....but has your dentist suggested a strong regime of anti-b's prior to the surgery.  With your history and background this would be pretty much S.O.P. and could prove to be very important.  If he has....great, no problem......  if he has not, then you may want to question that.   

My wife is a hygentist and she says many complications from oral surgery come on because folks like us (compromised immune systems) ...or people who have had recent surgeries..don't know or aren't told that they should be on anti-b's prior to and during the dental work.  Her office even suggests it if you are just coming in for a deep cleaning and have the issues I cited.

A dental infection is nothing to mess is so close to the brain and heart that infection into those areas is very common after major dental work.

dx IBS 1999   UC 2000   CD 2001
Tested BIOGEN TYSABRI (gave me 2 years of remission)
currently on Low Dose Netroxene (started Jan. 19, 2007)...against Dr's wishes, he was pushing for Remicade.  Stopped the Naltrexone July 28th...started Humira Aug 31st, 2007...current dose two shots every other week.
Crohns is currently active and has been since April of 2005
51 yrs old

Veteran Member

Date Joined Mar 2006
Total Posts : 501
   Posted 9/28/2007 8:36 AM (GMT -7)   
I just went in for a deep cleaning with root planing and scaling and got an infection after they did only one side of my mouth. They say I got an infection from tetracycline, but I think it's the herpes virus coming back that I had (oral herpes) 12 years ago.  I got hives on my face and small white bumps on the side they did the gum work.  Totally sucks, I have not done the other side as they want to wait, no one knows what it is.  I feel like a freak!
Diagnosed 1/06
CD of Terminal Ileum
Taking Pentasa, Prograf and Remicade.

Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 9/28/2007 8:39 PM (GMT -7)   

Yeah, I'm well aware of the release of bacteria into the bloodstream while undergoing dental work. That's part the reason I delayed some of the dental work until my CD was more settled and I got off the predinose. It was a gamble. I went to the ER the other night when 3 days after my Humira the dental situation occurred with no warning and swelled my mouth almost shut within 3 hours. I got to thinking...this infection is in my head and being very aggressive and I don't want to add meningitis to the list! The Dr. in the ER was smart to give me the Rociphen injection (he didn't play around), then a dental block (so my stomach didn't have to tolerate stronger pain killers prior to the antibiotics kickin in) and lastly followed up with 500mg, 3x a day of amoxicillin for 10 days (again, easier on the stomach). They are also planning to give me a bag or two of fluid IVs prior to surgery to help insure I don't dehydrate. The only thing I haven't covered at this point is a discussion with my GI about taking my scheduled Humira dose 2 days after the surgery....I'm apprehensive about that. Right now the GP says continue all meds as normal but I don't know if he's consulted with the GI yet. Thanks for your input'd be suprised at how many people are not aware of the need to be premedicated for "standard" dental procedures!
Dx'd Jan'06, 1st Resection 7/06, Predinsone, Humira, Imuran, B12 injections, Nexium. Secondary conditions: Psorasis, Acne, Fatigue, Joint Pain, Lactose Intolerant, gallstones, fibroid cysts, peri-menopausal.

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