acne from Remicade?

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Regular Member

Date Joined Jul 2005
Total Posts : 43
   Posted 10/3/2007 11:11 AM (GMT -7)   
I have been receiveing Remicade infusions since July, am now in my first 8 week period, and receiving my next infusion Friday (three days). I have developed what I guess is acne, though I've never had skin problems so I don't really know. I get small pimples around my hair line and most troubling are these patches of large, very sore pimples on both sides of my neck, below my ears. I've had several of these pimples on my neck for over a month now and have treated them topically but they won't go away! Has anyone experienced acne or skin eruptions of this type with Remicade or should I be suspecting something else? I'm on the verge of visiting the dermatologist, but I want to go armed with all the info. I can, if this is related to the Remicade. I'm also on Imuran 100mg daily, which Ive been taking for well over a year and never caused me skin problems before, so I highly suspect the Remi. but need confirmation. Thanks for any insights --

symptoms since college days thought to be IBS, now 34 - finally dxd with CD 3 years ago after colonscopy and SBFT. Have one great husband and 6 great kids, including two sets of boy/girl fraternal twins!

Regular Member

Date Joined Jul 2007
Total Posts : 137
   Posted 10/3/2007 11:39 AM (GMT -7)   
I have had similar problems along hairline and on my neck. Can't pinpoint when it started (I started remicade in december 06) but I had always just assumed it was the predisone since I have been on that the last couple months...hmmm...
Dx CD 2003 but probably had it 10 years prior
Dx Primary Sclerossing Cholangitis 2006
GB out '95, Appendix out '96, Kidney stent '02/stone removal '02, Resection '04, fistulectomy '06 2x, tubal '05
Currently on 100mg 6mp and Remicade every 8 weeks, Ambien as needed, predsnisone

Regular Member

Date Joined Dec 2006
Total Posts : 177
   Posted 10/3/2007 4:02 PM (GMT -7)   
Yes, I have had acne make a fuirious comeback since I started Remicade. My GI doesn't think it is a side effect, but I do, espeically when I get a bad break out after each infusion. I did some research at my school library and found an article in the British Journal of Dermatology about two documented cases of patients developing acne after being treated with Remicade- I can't find a link but it was sometime in the spring of 2007 that it was published. I'm on antibiotics (minocycline) to help the acne, but it hasn't gone away. Good luck.

Regular Member

Date Joined Jul 2003
Total Posts : 481
   Posted 10/3/2007 4:48 PM (GMT -7)   
I also never had skin problems in my life, and started having problems with acne after starting Remicade. I was also on a high dose of Prednisone at the time, so I was just hoping that was the problem since I'd be weaning off it. I really hope it isn't from the Remicade since I will probably be on that for a while. confused

Regular Member

Date Joined Jul 2005
Total Posts : 43
   Posted 10/3/2007 5:13 PM (GMT -7)   
Seems like a trend to me -- I had no hard eveidence but definitely a gut feeling that there's a connection between my infusions and these new breakouts. Ive wonderd if it had to do with immune system suppression that helps with the intestines, but may not be good for other parts of the body ...
Thanks to all who replied. I hope the conection is discovered and a way to prevent and/or treat the breakouts is made available. Until then, I'll be searching for something to knock out the pimples quickly. I'm 37 with 6 kids and too old to be dealing with this! Doesn't it always seem like what fixes one problem causes another?
symptoms since college days thought to be IBS, now 34 - finally dxd with CD 3 years ago after colonscopy and SBFT. Have one great husband and 6 great kids, including two sets of boy/girl fraternal twins!

Veteran Member

Date Joined Oct 2004
Total Posts : 3042
   Posted 10/3/2007 5:30 PM (GMT -7)   
Hi, I have been on Remicade for over 2 years and have no acne from the Remicade.
Good luck with your next infusion.
Hi, I am teddybearweiser, I am a male.
I was diagnosed with crohns disease when i was admitted to the hospital
in 1992, in Jan of 1993 I was back in the hospital for surgery for my crohns. I had part of my right colon resectioned with ilecolonstomy.
 My GI doctor has me on Asacol, Dicyclomine,Imuran,Celebrex and Remicade. B-12 injection once a month.
My Internest doctor has me on Lisnopril-HTCZ and Folic Acid. Diagnosed
with Osteoarthritis July 2007

Regular Member

Date Joined Jun 2005
Total Posts : 133
   Posted 10/4/2007 10:29 AM (GMT -7)   
i got what i thought was also acne, but started on my legs and eventually went everywhere except my face. after several docs, a infectious disease guy cultured it and found out to be fungal of some sort. still waiting to find out what strain for sure...
Diagnosed in 1999, hospitalized once.  Not responsive to meds.  Currently on 12 Asacol, , 8 ampules of Gastrocrom, 6 grams Colestid, flagyl, remicade for my UC.  Also have migraines and take B-4, B-2, for the prevention of them.
Deciding whether or not to have surgery at this time.

New Member

Date Joined Mar 2009
Total Posts : 1
   Posted 3/8/2009 4:29 AM (GMT -7)   
is this forum still on?

Regular Member

Date Joined Oct 2007
Total Posts : 149
   Posted 3/9/2009 5:34 AM (GMT -7)   
No problems here either, been on Remicade for 6 years now.
Crohns for 13 years
1 surgery so far
2 times in hospital for blockages
B12 Injections

Veteran Member

Date Joined Mar 2008
Total Posts : 1766
   Posted 3/9/2009 4:54 PM (GMT -7)   
I've had acne issues as well. I originally thought that the acne was from steroid rectal meds, but I've stopped it for almost two months and the acne remains. Given how strong this drug is, I'm not surprised that we're getting random side effects from it.
Female, Age 20
9 Asacol, Rowasa1000 mg Canasa, Proctofoam, Rifaximin 2/day
Digestive Advantage (Crohn's & Colitis)1 Florastor, 50 mg 6MP,1 Primadophilus reuteri, Remicade (6 infusions), 2.4 g Lialda, Forvia, 6 Colazal, 1 Anucort, Culturelle, Fish Oil, Calcium/Vit D supplement, 20 mg Prozac, VSL #3 DS, Turmeric

Charlotte Girl
New Member

Date Joined May 2009
Total Posts : 1
   Posted 5/5/2009 5:01 PM (GMT -7)   
I too started getting acne after getting remicade . It started on my face and chest and has recently moved to my back. My GI doctor also feels that it is not from the remicade. I don't know why all these GI doctors are in denial.

not creative
Regular Member

Date Joined Mar 2007
Total Posts : 469
   Posted 5/6/2009 9:03 AM (GMT -7)   
My remicade infusions caused rosacea...
Laurenne, 24 Graduate from University of California, Davis. BA-Anthropology
Dx'd w/ IBS and CD in 2002
On: 6MP, 20mg Prednisone, Zoloft, Lialda and Imodium
Tried: LDN- Did nothing good, Remicade- allergic, Humira- no reaction

Regular Member

Date Joined Oct 2008
Total Posts : 114
   Posted 5/6/2009 9:22 AM (GMT -7)   
I have been taking Remicade since November, 2008. I have noticed a major increase in the acne along my hair line, on my face and neck, and on my back and chest. I thought I had read somewhere (that I can't seem to find now) that acne of the face, neck, and back were a side effect of the remicade.

Diagnosed with Crohn's in July 2005. 2 Bowel Resections in 2008.
Currently taking Pentasa 1000 mg 4X/Day, 6MP 100 mg/day, multivitamin, Lopressor 100 mg/day (Blood Pressure), Remicade IV every 6 weeks, Omeprazole CR 40 mg/day, Percocet for pain, Lomotil, & Phenigren PRN

Regular Member

Date Joined Dec 2007
Total Posts : 131
   Posted 5/6/2009 10:45 AM (GMT -7)   
I've had a few breakouts, mostly on my shoulders and lower back however. They seem to take a while to heal. Not too bothersome, but I have noticed a slight increase in breakouts. To some extent, my body was so malnourished before it had kinda shut down. I suspect my hormones have returned as I have regained my health the last few months.
Type I Diabetes- 29 yrs. (MiniMed Insulin Pump)
Celiac Disease- 8 yrs.
Crohn's Disease- (Nov. '06)
Remicade (First Infusion 11/3/08) yeah

Forum Moderator

Date Joined Nov 2003
Total Posts : 7119
   Posted 5/6/2009 12:28 PM (GMT -7)   

For those of you that have developed skin issues while on Remicade or Humira and have doctors that poo-poo the possible connection-

Here's an article you can print out and take to them:

Serious skin reactions have been reported with tumor necrosis factor (TNF)–alpha antagonists, according to a March 18 US Food and Drug Administration (FDA) Drug Safety Newsletter.

Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Veteran Member

Date Joined Sep 2005
Total Posts : 769
   Posted 5/7/2009 6:49 PM (GMT -7)   
Well I hope it doesn't cause acne with me if I go on remicade! Guess I'll just have to wait and see, but I was on roaccutanne as a teen from acne and it scarred me for life! not just physically - I do NOT want acne again!!
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