Has anyone had problems with this drug? Both the gi NP and my regular NP suggested I try it because of my foot pain. I started at 50 mg. I had some immediate improvement but after a few doses felt like a new woman. then I thought it was making me a little quesy (sp?) so I cut back to 25 mg. Then I notice my blood pressure climbing. The last day I took it I felt great, on top of the world and my systolic bp was 165. So I stopped taking it, within about
36 hours my bp was normal again. (on one bp med) A little research and I found out that ultram is a very mild inhibitor of serotonin AND norepinephrine reuptake (same principal as the antidepressants, but some like paxil just targe serotonin. Some like cymbalta target both)
Does anyone have this problem with these drugs that also target norepinephrine? I feel like a freak. Half the world is on these drugs and I can't tolerate them. Cymbalta worked great for the foot pain. Tonight I start on 5 mg lexipro. I thought about trying ultram at 25mg and add acetominophen but now I understand that you can't take ultram and lexipro together.
I was not impressed with ambien. I thought that improved sleep (had a hard time falling asleep due to foot/leg pain) would improve the chronic pain. On 10 mg I fell asleep within 15 minutes, got about 5 hours of solid sleep, almost like anesthesia. If I took it at 10 pm-ish felt great the next day. If I took it at 1 am (like after work) I felt draggy.
Has lexipro helped anyone with chronic pain?