New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Regular Member

Date Joined Feb 2007
Total Posts : 74
   Posted 10/18/2007 8:03 PM (GMT -7)   



Question I also have been on Entocort Maintenance for some time but recently have been contemplainting going on Imuran.  I have some different people saying this is a better long term drug what are your thoughts .  It sounds to me like you have heard otherwise.

That which does not kill us makes us stronger.
Friedrich Nietzsche

Veteran Member

Date Joined Apr 2006
Total Posts : 1885
   Posted 10/18/2007 10:36 PM (GMT -7)   

Imuran is powerful and has been proven to cause mucosal healing...seems to stop Crohn's dead in its tracks.

Entocort is powerful but has not been proven to cause mucosal healing...so the question is, does it stop Crohn's dead in its tracks? Nobody knows. 

So I can see why many GIs feel it is safer to rely on Imuran to induce and maintain full remission...at a recent conference, a presenter said you might have to stay on it for at least five years. Nobody knows when you can safely stop Imuran.

We haven't chosen Imuran because:  

a) sure, it stops Crohn's, but it whacks the body's immune system...my daughter has always been susceptible to infection, so the last thing she needs is her immune system suppressed

b) in fact, the latest research does not support what GIs thought for years -- they thought Crohn's patients had overactive immune systems. instead, it seems they have underactive and inefficient immune systems  

c) LDN seems to offer promise as a safer med than Imuran, and preliminary evidence is that LDN does cause mucosal healing, so we are carefully watching those trials

d) we fear bone marrow suppression and all the other side effects -- even mesalamine seemed to exacerbate her propensity toward iron deficiency

Thanks to Entocort, my daughter is living her dream and studying abroad this Fall term. When she returns, we will have to think about doing a SBFT to figure out whether there is any Crohn's activity.

New Topic Post Reply Printable Version
Forum Information
Currently it is Tuesday, November 21, 2017 10:20 PM (GMT -7)
There are a total of 2,896,606 posts in 317,919 threads.
View Active Threads

Who's Online
This forum has 157505 registered members. Please welcome our newest member, Katy5990.
301 Guest(s), 14 Registered Member(s) are currently online.  Details
DBwithUC, Crispix, trainman456, notsosicklygirl, Spring, Satxmom, Charlie55, Sean.scott256, Yellow1955, Saipan Paradise, rockyfords, Katy5990, Margo78, Dirtfarmerswife

About Us | Advertise | Donate
Newsletter | Privacy Policy & Disclaimer
Follow HealingWell.com on Facebook Follow HealingWell.com on Twitter Follow HealingWell.com on Pinterest
©1996-2017 HealingWell.com LLC  All Rights Reserved.