Hello, I'm new to this forum and just have a couple questions. I'm 42, I've had daily moderate LRQ and mild to moderate LLQ pain for over 7 years, have had two lap surgeries in 2001 & 2002 to take down internal adhesions as we thought that was the source of the pain (appendix came out in 2002). Over the past three years have had occasional short flares of hand/joint pain. Have chronic low back pain all my adult life.
Any, in July the hand/joint pain flared with unusual intensity and hasn't stopped. At the same time the intestinal pain kicked up a few notches and I now have two more areas of pain in the upper right near the gallbladder and upper left. Since July I've been through ultrasounds, cat scans, blood tests and finally last week a colonoscopy, all negative. Blood work initially had a normal sed rate, last week's is slightly elevated at 24. GI changes over the last four months were increased bouts of alternating diarrhea/const. along with the increased pain and nausea, but no blood in the stool.
In consulting with the Rheumatologist he ran the Prometheus 7 test a couple weeks ago. It came back predictive for Chrohn's, with the Anti-CBir1 at 112.8 (normal range <21), IFA Perinuclear Pattern detected, and DNAse Sensitivity positive. The Rheum commented that to him this was a weak result, and if I had shown strongly positive in all areas he would have been more concerned, so we're on a wait and see and presuming it's IBS not IBD.
Do many docs out there put much stock in the Prometheus test? Do many of you go through ambiguous or negative test results only to come up positive later? Are there any other tests that might help get a clear picture?
My approach right now is to eat better, excercise more, etc. and hope to start feeling better. I remain concerned though, because I just recently tested positive for another AI disease (Hashimoto's), plus I have a sister and two nieces with Crohn's, sister with Lupus, a two other relatives with MS & UC.
Sorry this is so long, I look forward to hearing any feedback you might have...... Thanks!