Welcome to Healing Well! Question for you - did you have a Roux-en-Y type gastric bypass? That is the most commonly performed type of weight loss surgery. In that surgery the top of the stomach is stapled creating a small pouch and the small intestine is attached to that small pounch. Food enters directly into the second section of your small intestine, the jejunum.
As far as where and how various meds work, from the prescribing info for Liada:
The tablet is coated with a gastro-resistant pH dependent polymer film, which breaks down at or above pH 7, normally in the terminal ileum where mesalamine then begins to be released from the tablet core. So it is designed to release in the terminal ileum which is below your jejunum. The question then becomes, is the pH in your ileum altered by the bypass? I think perhaps the bypass surgeon might know the answer to this since the GI doesn't.
Pentasa is designed to release throughout the intestinal tract. I could not find specifics of release parameters. If the Pentasa is working for you but you are having trouble remembering to take the pills, perhaps a watch with an alarm. Or what about
a small divided daily pill container that you keep with you? Those are very inexpensive at the drugstore.
There used to be a good article about
the role of diet in Crohn's disease on the Internet. The page is no longer available but I have a copy of it. If you would like me to email it to you, please contact me. My email addy is available to the left under my name in the blue envelope icon.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, diffuse connective tissue disease, Sjogren's Syndrome ?